Reaction profile

The FDA adverse-event record for thrombocytopenia

4,205 FDA reports name thrombocytopenia, a high-volume reaction in the CVM extract (VeDDRA 160). Plate stamps and neighbourhood peers follow.

#112 of 2,481
by report volume (all reactions)
4,205
reports citing this reaction
32.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Thrombocytopenia has 4,205 reports now versus 4,130 in that prior snapshot: 75 more (1.8%).

Report change
+75
Death-coded reports
+15
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Thrombocytopenia changes

FDA AER · VeDDRA plate

Code 160 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 4,205 reports
  • DEATH-HOT 32.7%
  • TOP-DECILE #112/2481
  • PHOTO-FINISH Malaise
  • SPECIES-DOG Dog · 3,675
  • DRUG-LEAD Carprofen · 598
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Malaise (±40 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Thrombocytopenia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Thrombocytopenia · this reac…4205Malaise · near4165Reddening of the skin · near4123Reluctant to move · near4123Hypoglycaemia · near4092Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Thrombocytopenia

Thrombocytopenia: high death-coded share in the FDA AER plate

Signature read: 1,374 death-coded reports is a heavy tail count for Thrombocytopenia in the CVM extract. Report volume is upper-third scale: 4,205 named reports in the openFDA extract. Death-coded share is upper-third: 1,374 of 4,205 reports (32.7% of named reports). Nearest volume peer: Malaise (±40 reports). Lead species Dog (3,675). Lead co-reported drug Carprofen (598).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 3,675
Cat 500
Horse 23
Human 2
Rabbit 1
Alpaca 1
Marsupial 1
Monkey 1
Other Mammals 1

Breeds Most Affected

Retriever - Labrador 483
Crossbred Canine/dog 293
Domestic Shorthair 260
Retriever - Golden 216
Shepherd Dog - German 156
Chihuahua 115
Boxer (German Boxer) 106
Shih Tzu 102
Domestic (unspecified) 78
Terrier - Yorkshire 78

Associated Drugs

Carprofen 598
Maropitant Citrate 459
Moxidectin 350
Oclacitinib Maleate 349
Prednisone 264
Afoxolaner 246
Milbemycin Oxime + Spinosad 245
Cefovecin 237
Bedinvetmab 181
Doxycycline 180
Gabapentin 167
Fluralaner Chew Tablets 152
Meloxicam 149
Famotidine 138
Metronidazole 130
Enrofloxacin 129
Deracoxib 120
Dexamethasone 119
Spinosad 109
Pyrantel Pamoate;Sarolaner 108

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Thrombocytopenia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (4,205 here).

Similar death-coded share

Nearest other reactions by death-coded share (32.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Thrombocytopenia (#112 of 2,481 by report volume); death-coded 32.7%. PlainBreed reaction plate · death-coded report count stamp 1,374 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →