Thrombocytopenia

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VeDDRA Code: 160

4,035 adverse event reports referencing this reaction

4,035
Total Reports
1,320
Deaths
3270.0%
Death Rate

Species Most Affected

Dog 3,543
Cat 464
Horse 21
Human 2
Rabbit 1
Alpaca 1
Marsupial 1
Monkey 1
Other Mammals 1

Breeds Most Affected

Retriever - Labrador 460
Crossbred Canine/dog 281
Domestic Shorthair 236
Retriever - Golden 207
Shepherd Dog - German 145
Chihuahua 104
Boxer (German Boxer) 103
Shih Tzu 99
Domestic (unspecified) 78
Terrier - Yorkshire 75

Associated Drugs

Carprofen 581
Maropitant Citrate 412
Moxidectin 340
Oclacitinib Maleate 336
Prednisone 249
Milbemycin Oxime + Spinosad 245
Afoxolaner 242
Cefovecin 230
Doxycycline 170
Bedinvetmab 169
Fluralaner Chew Tablets 152
Gabapentin 143
Meloxicam 141
Famotidine 127
Enrofloxacin 119
Deracoxib 117
Dexamethasone 114
Metronidazole 113
Spinosad 109
Ivermectin + Pyrantel As Pamoate Salt 99

Data Summary

Metric Value
Total reports referencing reaction 4,035
Reports with fatal outcome 1,320
Case-fatality rate (reported events) 3270.0%
Species observed 9
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 160.

Thrombocytopenia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 4,035 adverse event reports that reference Thrombocytopenia as a reaction term, including 1,320 reports with a death outcome — a 3270.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 160, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Thrombocytopenia appears most frequently in reports for Dog (3,543 reports), Cat (464 reports), Horse (21 reports) — with Dog dominating at 3,543 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (460), Crossbred Canine/dog (281), Domestic Shorthair (236). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Thrombocytopenia are Carprofen (581 reports), Maropitant Citrate (412 reports), Moxidectin (340 reports), Oclacitinib Maleate (336 reports), with Carprofen appearing alongside this reaction in 581 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial