Neuropathy NOS

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VeDDRA Code: 1650

149 adverse event reports referencing this reaction

149
Total Reports
32
Deaths
2150.0%
Death Rate

Species Most Affected

Dog 106
Cat 39
Horse 2
Human 2

Breeds Most Affected

Domestic Shorthair 21
Retriever - Labrador 17
Dog (unknown) 10
Retriever - Golden 7
Shepherd Dog - German 7
Pit Bull 3
Terrier - Bull - American Pit 3
Unknown 3
Collie - Border 3
Poodle (unspecified) 3

Associated Drugs

Bedinvetmab 43
Gabapentin 19
Carprofen 15
Frunevetmab 11
Maropitant Citrate 10
Bexagliflozin 10
Oclacitinib Maleate 8
Pyrantel Pamoate;Sarolaner 8
Galliprant 8
Milbemycin Oxime + Spinosad 7
Afoxolaner 6
Adequan 6
Dasuquin 6
Fluralaner Chew Tablets 5
Imidocarb Dipropionate Inj Sol 5
Ivermectin 4
Rabies Virus, Kv 4
Sarolaner 4
Cefovecin 3
Insulin Injectable Vial 3

Data Summary

Metric Value
Total reports referencing reaction 149
Reports with fatal outcome 32
Case-fatality rate (reported events) 2150.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1650.

Neuropathy NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 149 adverse event reports that reference Neuropathy NOS as a reaction term, including 32 reports with a death outcome — a 2150.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1650, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Neuropathy NOS appears most frequently in reports for Dog (106 reports), Cat (39 reports), Horse (2 reports) — with Dog dominating at 106 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (21), Retriever - Labrador (17), Dog (unknown) (10). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Neuropathy NOS are Bedinvetmab (43 reports), Gabapentin (19 reports), Carprofen (15 reports), Frunevetmab (11 reports), with Bedinvetmab appearing alongside this reaction in 43 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial