Poor coat condition

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VeDDRA Code: 1996

216 adverse event reports referencing this reaction

216
Total Reports
21
Deaths
970.0%
Death Rate

Species Most Affected

Dog 131
Cat 40
Cattle 37
Horse 6
Bison 1
Other Equids 1

Breeds Most Affected

Domestic Shorthair 22
Retriever - Labrador 15
Shepherd Dog - German 12
Retriever - Golden 9
Holstein-Friesian also known as Holstein 7
Aberdeen Angus 7
Cattle (other) 7
Crossbred Canine/dog 7
Domestic Longhair 6
Crossbred Bovine/Cattle 6

Associated Drugs

Trilostane 58
Milbemycin Oxime + Spinosad 22
Eprinomectin 5% Injection 11
Afoxolaner 11
Prednisone 9
Fluralaner Chew Tablets 9
Moxidectin 8
Bexagliflozin 8
Spinosad 7
Buprenorphine 6
Ivermectin 6
Levothyroxine Sodium 6
Maropitant Citrate 6
Gabapentin 6
Selamectin 5
Carprofen 5
Eprinomectin 5 Mg/Ml Pour-On Solution 5
Merial La Polypropylene Syringe 5
Doxycycline 5
Portech App Gun 65 Ml Ivomec/Eprinex 5

Data Summary

Metric Value
Total reports referencing reaction 216
Reports with fatal outcome 21
Case-fatality rate (reported events) 970.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1996.

Poor coat condition Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 216 adverse event reports that reference Poor coat condition as a reaction term, including 21 reports with a death outcome — a 970.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1996, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Poor coat condition appears most frequently in reports for Dog (131 reports), Cat (40 reports), Cattle (37 reports) — with Dog dominating at 131 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (22), Retriever - Labrador (15), Shepherd Dog - German (12). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Poor coat condition are Trilostane (58 reports), Milbemycin Oxime + Spinosad (22 reports), Eprinomectin 5% Injection (11 reports), Afoxolaner (11 reports), with Trilostane appearing alongside this reaction in 58 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial