Elevated haematocrit

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VeDDRA Code: 2856

247 adverse event reports referencing this reaction

247
Total Reports
35
Deaths
1420.0%
Death Rate

Species Most Affected

Dog 219
Cat 27
Horse 1

Breeds Most Affected

Retriever - Labrador 28
Crossbred Canine/dog 21
Terrier - Yorkshire 12
Domestic Shorthair 12
Chihuahua 11
Shepherd Dog - German 9
Beagle 8
Terrier - Bull - American Pit 8
Shepherd Dog - Australian 7
Boxer (German Boxer) 6

Associated Drugs

Maropitant Citrate 35
Carprofen 29
Gabapentin 25
Metronidazole 22
Bedinvetmab 21
Fluralaner 13.64% 12-Week Chew 20
Afoxolaner 20
Moxidectin 19
Milbemycin Oxime + Praziquantel 17
Enrofloxacin 17
Famotidine 14
Butorphanol 14
Lotilaner 13
Propofol 12
Rabies Vaccine 12
Pyrantel Pamoate;Sarolaner 10
Anti-Il31 Mab Mcs Lot #1283563 10
Prednisone 10
Fluid Therapy 10
Oclacitinib Maleate 10

Data Summary

Metric Value
Total reports referencing reaction 247
Reports with fatal outcome 35
Case-fatality rate (reported events) 1420.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2856.

Elevated haematocrit Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 247 adverse event reports that reference Elevated haematocrit as a reaction term, including 35 reports with a death outcome — a 1420.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2856, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Elevated haematocrit appears most frequently in reports for Dog (219 reports), Cat (27 reports), Horse (1 reports) — with Dog dominating at 219 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (28), Crossbred Canine/dog (21), Terrier - Yorkshire (12). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Elevated haematocrit are Maropitant Citrate (35 reports), Carprofen (29 reports), Gabapentin (25 reports), Metronidazole (22 reports), with Maropitant Citrate appearing alongside this reaction in 35 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

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Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial