Reaction profile

The FDA adverse-event record for reduced faecal output

42 FDA adverse-event reports reference reduced faecal output (VeDDRA 2678). See the species, breeds, and drugs most associated with it below.

42
reports citing this reaction
7.1%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
42
Total Reports
3
Deaths
7.1%
Death Rate

Species Most Affected

Dog 24
Cat 14
Horse 2
Rabbit 2

Breeds Most Affected

Domestic Shorthair 10
Chihuahua 3
Domestic Longhair 3
Poodle - Toy 2
Spaniel (unspecified) 2
Maltese 2
Retriever - Labrador 2
Cat (other) 1
Terrier - Bull 1
Anglo Arab 1

Associated Drugs

Maropitant Citrate 5
Carprofen 5
Pyrantel Pamoate;Sarolaner 4
Buprenorphine 4
Cefovecin 3
Trilostane 3
Fluralaner 13.64% 12-Week Chew 3
Ivermectin + Pyrantel As Pamoate Salt 3
Frunevetmab 3
Selamectin;Sarolaner 2
Omeprazole 2
Amoxicillin 2
Ursodiol 2
Capromorelin Oral Solution 2
Probiotic Supplement 2
Trazodone 2
Afoxolaner 1
Lufenuron + Milbemycin Oxime + Praziquantel 1
Methylprednisolone Acetate 1
Milbemycin Oxime & Lufenuron 1

Reduced faecal output Reaction Insights

42 reports name Reduced faecal output; 3 recorded a death outcome (7.1% of reported events, not a population-level mortality rate). VeDDRA code: 2678.

By species: Dog (24 reports), Cat (14 reports), Horse (2 reports). By breed: Domestic Shorthair (10), Chihuahua (3), Domestic Longhair (3).

Most co-reported drugs: Maropitant Citrate (5 reports), Carprofen (5 reports), Pyrantel Pamoate;Sarolaner (4 reports), Buprenorphine (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.