Reaction profile

The FDA adverse-event record for multiple organ haemorrhage

38 FDA reports name multiple organ haemorrhage, a lower-volume reaction in the CVM extract (VeDDRA 2097). Plate stamps and neighbourhood peers follow.

#1881 of 2,481
by report volume (all reactions)
38
reports citing this reaction
100.0%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Multiple organ haemorrhage has 38 reports now versus 38 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Multiple organ haemorrhage changes

FDA AER · VeDDRA plate

Code 2097 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 38 reports
  • DEATH-HOT 100.0%
  • LOWER-Q #1881/2481
  • PHOTO-FINISH Clenched jaw
  • SPECIES-DOG Dog · 31
  • DRUG-LEAD Milbemycin Oxime… · 20
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Multiple organ haemorrhage

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Clenched jaw · near38Conjunctival reddening · near38Disturbance in attent… · near38Duodenitis · near38Multiple organ haemor… · thi…38Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Multiple organ haemorrhage

Multiple organ haemorrhage: high death-coded share in the FDA AER plate

Signature read: Multiple organ haemorrhage's 100.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 38 named reports in the openFDA extract. Death-coded share is upper-third: 38 of 38 reports (100.0% of named reports). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (31). Lead co-reported drug Milbemycin Oxime + Spinosad (20).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 31
Cat 5
Cattle 1
Horse 1

Breeds Most Affected

Shepherd Dog - German 6
Retriever - Labrador 5
Domestic Shorthair 4
Collie - Border 2
Shih Tzu 2
Dachshund (unspecified) 1
Schnauzer (unspecified) 1
Siberian Husky 1
Terrier - Jack Russell 1
Crossbred Canine/dog 1

Associated Drugs

Milbemycin Oxime + Spinosad 20
Carprofen 3
Maropitant Citrate 3
Doxycycline 2
Ivermectin 2
Prednisone 2
Rabies Vaccine 2
Moxidectin 2
Dexmedetomidine 2
Butorphanol 2
Ketamine 2
Lyme Vaccine 2
Fluralaner Powder For Inj Susp 2
Spinosad 1
Heartworm Prevention (Unknown) 1
Hydroxyzine 1
Ivermectin 68Mcg, Pyrantel Pamoate 57Mg, Praziquantel 57Mg 1
Deracoxib 1
Dexmedetomidine, Butorphanol 1
Lufenuron + Milbemycin Oxime 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Multiple organ haemorrhage (#1881 of 2,481 by report volume); death-coded 100.0%. PlainBreed reaction plate · death-coded share stamp 100.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →