Reaction profile

The FDA adverse-event record for spondylosis

331 FDA adverse-event reports reference spondylosis (VeDDRA 1788). See the species, breeds, and drugs most associated with it below.

331
reports citing this reaction
24.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
331
Total Reports
82
Deaths
24.8%
Death Rate

Species Most Affected

Dog 309
Cat 22

Breeds Most Affected

Retriever - Labrador 58
Shepherd Dog - German 28
Crossbred Canine/dog 13
Retriever - Golden 13
Boxer (German Boxer) 12
Domestic Shorthair 12
Siberian Husky 10
Chihuahua 8
Terrier - Bull - American Pit 8
Rottweiler 8

Associated Drugs

Bedinvetmab 108
Carprofen 56
Gabapentin 51
Milbemycin Oxime + Spinosad 40
Oclacitinib Maleate 29
Grapiprant 29
Trilostane 21
Maropitant Citrate 18
Prednisone 17
Meloxicam 15
Moxidectin 14
Fluralaner Chew Tablets 14
Enrofloxacin 13
Famotidine 12
Afoxolaner 12
Metronidazole 11
Fluralaner 13.64% 12-Week Chew 11
Frunevetmab 11
Cefovecin 9
Anti-Il31 Mab Mcs Lot #1283563 9

Spondylosis Reaction Insights

331 reports name Spondylosis; 82 recorded a death outcome (24.8% of reported events, not a population-level mortality rate). VeDDRA code: 1788.

By species: Dog (309 reports), Cat (22 reports). By breed: Retriever - Labrador (58), Shepherd Dog - German (28), Crossbred Canine/dog (13).

Most co-reported drugs: Bedinvetmab (108 reports), Carprofen (56 reports), Gabapentin (51 reports), Milbemycin Oxime + Spinosad (40 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.