Reaction profile

The FDA adverse-event record for spondylosis

371 FDA reports name spondylosis, a high-volume reaction in the CVM extract (VeDDRA 1788). Plate stamps and neighbourhood peers follow.

#774 of 2,481
by report volume (all reactions)
371
reports citing this reaction
25.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Spondylosis has 371 reports now versus 356 in that prior snapshot: 15 more (4.2%).

Report change
+15
Death-coded reports
+4
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Spondylosis changes

FDA AER · VeDDRA plate

Code 1788 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 371 reports
  • DEATH-HOT 25.6%
  • MID-PACK #774/2481
  • PHOTO-FINISH Headache
  • SPECIES-DOG Dog · 341
  • DRUG-LEAD Bedinvetmab · 130
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Headache (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Spondylosis

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lung oedema · near373Platelet disorder NOS · near373Headache · near372Spondylosis · this reaction371Blood and lymphatic s… · near369Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Spondylosis

Spondylosis: high death-coded share in the FDA AER plate

Signature read: 95 death-coded reports is a heavy tail count for Spondylosis in the CVM extract. Report volume is upper-third scale: 371 named reports in the openFDA extract. Death-coded share is upper-third: 95 of 371 reports (25.6% of named reports). Nearest volume peer: Headache (±1 reports). Lead species Dog (341). Lead co-reported drug Bedinvetmab (130).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 341
Cat 30

Breeds Most Affected

Retriever - Labrador 67
Shepherd Dog - German 33
Retriever - Golden 17
Domestic Shorthair 15
Crossbred Canine/dog 13
Boxer (German Boxer) 13
Terrier - Bull - American Pit 11
Siberian Husky 10
Chihuahua 8
Rottweiler 8

Associated Drugs

Bedinvetmab 130
Carprofen 65
Gabapentin 64
Milbemycin Oxime + Spinosad 41
Oclacitinib Maleate 31
Grapiprant 31
Maropitant Citrate 22
Trilostane 21
Frunevetmab 19
Meloxicam 18
Prednisone 18
Moxidectin 15
Enrofloxacin 14
Fluralaner Chew Tablets 14
Afoxolaner 13
Famotidine 12
Fluralaner 13.64% 12-Week Chew 12
Anti-Il31 Mab Mcs Lot #1283563 12
Metronidazole 11
Cefovecin 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Spondylosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (371 here).

Similar death-coded share

Nearest other reactions by death-coded share (25.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Spondylosis (#774 of 2,481 by report volume); death-coded 25.6%. PlainBreed reaction plate · death-coded report count stamp 95 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →