Reaction profile

The FDA adverse-event record for ear pruritus

342 FDA adverse-event reports reference ear pruritus (VeDDRA 2573). See the species, breeds, and drugs most associated with it below.

342
reports citing this reaction
2.0%
death-coded share
Dog
most-affected species
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride
most-associated drug
Verify with FDA CVM →
342
Total Reports
7
Deaths
2.0%
Death Rate

Species Most Affected

Dog 234
Cat 108

Breeds Most Affected

Domestic Shorthair 74
Retriever - Labrador 21
Crossbred Canine/dog 20
Dog (unknown) 18
Shih Tzu 15
Retriever - Golden 9
Shepherd Dog - German 8
Pit Bull 8
Chihuahua 8
Terrier - Jack Russell 8

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 85
Frunevetmab 37
Imidacloprid + Moxidectin 31
Afoxolaner 24
Oclacitinib Maleate 21
Prednisone 15
Milbemycin Oxime + Praziquantel 14
Pyrantel Pamoate;Sarolaner 14
Milbemycin Oxime + Spinosad 13
Enrofloxacin 12
Maropitant Citrate 12
Ear Cleaner 12
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 11
Moxidectin 10
Oclacitinib 9
Selamectin 9
Genta/Momet/Clotrim Ear Oint 7
Otic Cleanser 6
Grapiprant 6
Carprofen 6

Ear pruritus Reaction Insights

342 reports name Ear pruritus; 7 recorded a death outcome (2.0% of reported events, not a population-level mortality rate). VeDDRA code: 2573.

By species: Dog (234 reports), Cat (108 reports). By breed: Domestic Shorthair (74), Retriever - Labrador (21), Crossbred Canine/dog (20).

Most co-reported drugs: Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (85 reports), Frunevetmab (37 reports), Imidacloprid + Moxidectin (31 reports), Afoxolaner (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.