Cutaneous emphysema

Verify with FDA CVM →

VeDDRA Code: 1202

40 adverse event reports referencing this reaction

40
Total Reports
16
Deaths
4000.0%
Death Rate

Species Most Affected

Dog 16
Cat 13
Cattle 10
Horse 1

Breeds Most Affected

Domestic Shorthair 9
Cattle (other) 5
Jersey 2
Domestic Longhair 2
Boxer (German Boxer) 2
Holstein-Friesian also known as Holstein 1
Shih Tzu 1
Aberdeen Angus 1
Maine Coon 1
Dog (unknown) 1

Associated Drugs

Dinoprost Tromethamine 7
Cefovecin 6
Maropitant Citrate 5
Robenacoxib 4
Clostridium Novyi, 8296;Clostridium Perfringens Type C, Pc8 4
Dexamethasone 3
Rabies Vaccine 2
Diphenhydramine Hcl 2
Dexmedetomidine Hydrochloride 2
Selamectin 2
Butorphanol Tartrate 2
Ketamine 2
Isoflurane 2
Moxidectin 2
Bupivacaine 2
Carprofen 2
Prednisone 2
Anesthetic 2
Praziquantel And Pyrantel Pamoate 1
Ceftiofur Crystalline Free Acid 1

Data Summary

Metric Value
Total reports referencing reaction 40
Reports with fatal outcome 16
Case-fatality rate (reported events) 4000.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1202.

Cutaneous emphysema Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 40 adverse event reports that reference Cutaneous emphysema as a reaction term, including 16 reports with a death outcome — a 4000.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1202, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Cutaneous emphysema appears most frequently in reports for Dog (16 reports), Cat (13 reports), Cattle (10 reports) — with Dog dominating at 16 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (9), Cattle (other) (5), Jersey (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Cutaneous emphysema are Dinoprost Tromethamine (7 reports), Cefovecin (6 reports), Maropitant Citrate (5 reports), Robenacoxib (4 reports), with Dinoprost Tromethamine appearing alongside this reaction in 7 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial