Reaction profile

The FDA adverse-event record for prolonged anaesthesia

71 FDA adverse-event reports reference prolonged anaesthesia (VeDDRA 1218). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1571 of 2,481
by report volume (all reactions)
71
reports citing this reaction
16.9%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Prolonged anaesthesia has 71 reports now versus 69 in that prior snapshot: 2 more (2.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Prolonged anaesthesia changes

FDA AER · VeDDRA plate

Code 1218 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 71 reports
  • DEATH-ELEV 16.9%
  • MID-PACK #1571/2481
  • PHOTO-FINISH Administration device…
  • SPECIES-CAT Cat · 34
  • DRUG-LEAD Isoflurane · 14
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Administration device NOS, missing component (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Prolonged anaesthesia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Administration device… · near71Application site thic… · near71Blotchy rash · near71Enlarged pupils · near71Prolonged anaesthesia · this…71Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Prolonged anaesthesia

What the FDA AER plate says about Prolonged anaesthesia

Signature read: report volume at 71 (#1571 of 2,481) is the standout scale stamp on Prolonged anaesthesia. Report volume sits in the middle third of the reaction corpus. 12 of 71 reports were death-coded (16.9% of named reports, not a population mortality rate). Nearest volume peer: Administration device NOS, missing component (±0 reports). Lead species Cat (34). Lead co-reported drug Isoflurane (14).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Isoflurane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 34
Dog 28
Horse 4
Turtle 1
Other 1
Mouse 1
Rabbit 1
Donkey 1

Breeds Most Affected

Domestic Shorthair 18
Domestic (unspecified) 6
Unknown 6
Cat (unknown) 5
Crossbred Canine/dog 4
Dog (unknown) 4
Mixed (Dog) 2
Terrier - Yorkshire 2
Retriever - Labrador 2
Quarter Horse 2

Associated Drugs

Isoflurane 14
Butorphanol 14
Propofol 14
Alfaxalone 10
Buprenorphine 9
Ketamine 7
Dexmedetomidine Hydrochloride 6
Ketamine Hydrochloride 5
Butorphanol Tartrate 5
Dexmedetomidine 5
Maropitant Citrate 4
Midazolam 4
Device: Surgical Instruments 3
Xylazine 3
Robenacoxib 3
Atipamezole Hydrochloride 3
Fluralaner Chew Tablets 3
Oxygen 3
Tiletamine, Zolazepam 2
Acepromazine Maleate 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Prolonged anaesthesia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (16.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Prolonged anaesthesia (#1571 of 2,481 by report volume); death-coded 16.9%. PlainBreed reaction plate · report volume stamp 71 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →