Reaction profile

The FDA adverse-event record for nephritis

99 FDA adverse-event reports reference nephritis (VeDDRA 714). See the species, breeds, and drugs most associated with it below.

99
reports citing this reaction
59.6%
death-coded share
Dog
most-affected species
Maropitant Citrate
most-associated drug
Verify with FDA CVM →
99
Total Reports
59
Deaths
59.6%
Death Rate

Species Most Affected

Dog 68
Cat 29
Other Birds 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 10
Crossbred Canine/dog 6
Retriever - Golden 6
Cat (unknown) 5
Domestic (unspecified) 4
Domestic Mediumhair 3
Bichon Frise 2
Pinscher - Miniature 2
Terrier - Jack Russell 2

Associated Drugs

Maropitant Citrate 12
Milbemycin Oxime + Spinosad 11
Meloxicam 10
Spinosad 9
Buprenorphine 8
Carprofen 7
Gabapentin 7
Oclacitinib Maleate 7
Moxidectin 6
Fluralaner Chew Tablets 5
Doxycycline 5
Enrofloxacin 5
Deracoxib 4
Ketamine 4
Dexmedetomidine 4
Afoxolaner 4
Milbemycin Oxime + Praziquantel 4
Capromorelin Tartrate 4
Cyclosporine 3
Prednisone 3

Nephritis Reaction Insights

99 reports name Nephritis; 59 recorded a death outcome (59.6% of reported events, not a population-level mortality rate). VeDDRA code: 714.

By species: Dog (68 reports), Cat (29 reports), Other Birds (1 reports). By breed: Domestic Shorthair (12), Retriever - Labrador (10), Crossbred Canine/dog (6).

Most co-reported drugs: Maropitant Citrate (12 reports), Milbemycin Oxime + Spinosad (11 reports), Meloxicam (10 reports), Spinosad (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.