Reaction profile

The FDA adverse-event record for seroma

95 FDA adverse-event reports reference seroma (VeDDRA 963). See the species, breeds, and drugs most associated with it below.

95
reports citing this reaction
12.6%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
95
Total Reports
12
Deaths
12.6%
Death Rate

Species Most Affected

Dog 66
Cat 17
Cattle 5
Rabbit 4
Horse 2
Unknown 1

Breeds Most Affected

Retriever - Labrador 13
Domestic Shorthair 8
Crossbred Canine/dog 6
Shepherd Dog - German 5
Doberman Pinscher 3
Retriever - Golden 3
Boxer (German Boxer) 3
Terrier (unspecified) 3
Terrier - Boston 3
Holstein-Friesian also known as Holstein 3

Associated Drugs

Carprofen 22
Meloxicam 15
Isoflurane 12
Buprenorphine 9
Melarsomine Dihydrochloride 9
Maropitant Citrate 8
Propofol 7
Butorphanol 7
Robenacoxib 7
Tramadol 6
Midazolam 6
Gabapentin 6
Cefpodoxime Proxetil 5
Enrofloxacin 5
Dexmedetomidine Hydrochloride 4
Prednisone 4
Deracoxib 4
Cefovecin 4
Milbemycin Oxime + Spinosad 4
Hydromorphone 4

Seroma Reaction Insights

95 reports name Seroma; 12 recorded a death outcome (12.6% of reported events, not a population-level mortality rate). VeDDRA code: 963.

By species: Dog (66 reports), Cat (17 reports), Cattle (5 reports). By breed: Retriever - Labrador (13), Domestic Shorthair (8), Crossbred Canine/dog (6).

Most co-reported drugs: Carprofen (22 reports), Meloxicam (15 reports), Isoflurane (12 reports), Buprenorphine (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.