Reaction profile

The FDA adverse-event record for haemangiosarcoma

198 FDA adverse-event reports reference haemangiosarcoma (VeDDRA 2072). See the species, breeds, and drugs most associated with it below.

198
reports citing this reaction
63.6%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
198
Total Reports
126
Deaths
63.6%
Death Rate

Species Most Affected

Dog 193
Cat 5

Breeds Most Affected

Retriever - Labrador 27
Retriever - Golden 25
Dog (unknown) 15
Crossbred Canine/dog 13
Shepherd Dog - German 13
Terrier - Bull - American Pit 10
Shepherd Dog - Australian 9
Beagle 5
Poodle - Standard 5
Domestic Shorthair 4

Associated Drugs

Oclacitinib Maleate 50
Milbemycin Oxime + Spinosad 31
Carprofen 19
Milbemycin Oxime + Praziquantel 14
Trilostane 11
Maropitant Citrate 10
Polysulfated Glycosaminoglycan 9
Cyclosporine 9
Gabapentin 8
Afoxolaner 8
Grapiprant 8
Fluralaner 13.64% 12-Week Chew 7
Cyclosporine A 6
Fluralaner Chew Tablets 6
Ivermectin + Pyrantel As Pamoate Salt 6
Anti-Il31 Mab Mcs Lot #1283563 6
Spinosad 5
Metronidazole 5
Firocoxib 227 Mg Chewable 4
Firocoxib 4

Haemangiosarcoma Reaction Insights

198 reports name Haemangiosarcoma; 126 recorded a death outcome (63.6% of reported events, not a population-level mortality rate). VeDDRA code: 2072.

By species: Dog (193 reports), Cat (5 reports). By breed: Retriever - Labrador (27), Retriever - Golden (25), Dog (unknown) (15).

Most co-reported drugs: Oclacitinib Maleate (50 reports), Milbemycin Oxime + Spinosad (31 reports), Carprofen (19 reports), Milbemycin Oxime + Praziquantel (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.