Reaction profile

The FDA adverse-event record for microorganisms, urine

321 FDA adverse-event reports reference microorganisms, urine (VeDDRA 99284). See the species, breeds, and drugs most associated with it below.

321
reports citing this reaction
20.6%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
321
Total Reports
66
Deaths
20.6%
Death Rate

Species Most Affected

Dog 279
Cat 40
Horse 1
Squirrel 1

Breeds Most Affected

Retriever - Labrador 39
Crossbred Canine/dog 33
Domestic Shorthair 17
Retriever - Golden 15
Shih Tzu 11
Domestic (unspecified) 10
Beagle 10
Terrier - Yorkshire 8
Boxer (German Boxer) 8
Bichon Frise 7

Associated Drugs

Trilostane 54
Oclacitinib Maleate 52
Carprofen 31
Deracoxib 22
Milbemycin Oxime + Spinosad 16
Maropitant Citrate 14
Afoxolaner 14
Moxidectin 13
Insulin Injectable Vial 13
Meloxicam 12
Enrofloxacin 12
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 11
Firocoxib 10
Cyclosporine 9
Cefovecin 9
Selamectin 8
Famotidine 8
Tramadol 8
Fluralaner Chew Tablets 8
Ivermectin + Pyrantel As Pamoate Salt 7

MICROORGANISMS, URINE Reaction Insights

321 reports name MICROORGANISMS, URINE; 66 recorded a death outcome (20.6% of reported events, not a population-level mortality rate). VeDDRA code: 99284.

By species: Dog (279 reports), Cat (40 reports), Horse (1 reports). By breed: Retriever - Labrador (39), Crossbred Canine/dog (33), Domestic Shorthair (17).

Most co-reported drugs: Trilostane (54 reports), Oclacitinib Maleate (52 reports), Carprofen (31 reports), Deracoxib (22 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.