Reaction profile

The FDA adverse-event record for microorganisms, urine

325 FDA adverse-event reports reference microorganisms, urine (VeDDRA 99284). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#838 of 2,481
by report volume (all reactions)
325
reports citing this reaction
20.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. MICROORGANISMS, URINE has 325 reports now versus 324 in that prior snapshot: 1 more (0.3%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to MICROORGANISMS, URINE changes

FDA AER · VeDDRA plate

Code 99284 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 325 reports
  • DEATH-HOT 20.6%
  • MID-PACK #838/2481
  • PHOTO-FINISH Deafness NOS
  • SPECIES-DOG Dog · 282
  • DRUG-LEAD Trilostane · 55
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Deafness NOS (±1 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around MICROORGANISMS, URINE

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Ear canal erythema · near328Irregular breathing · near326MICROORGANISMS, URINE · this…325Deafness NOS · near324Implant, Abnormal · near322Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around MICROORGANISMS, URINE

What the FDA AER plate says about MICROORGANISMS, URINE

Signature read: 67 death-coded reports is a heavy tail count for MICROORGANISMS, URINE in the CVM extract. Report volume sits in the middle third of the reaction corpus. 67 of 325 reports were death-coded (20.6% of named reports, not a population mortality rate). Nearest volume peer: Deafness NOS (±1 reports). Lead species Dog (282). Lead co-reported drug Trilostane (55).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 282
Cat 41
Horse 1
Squirrel 1

Breeds Most Affected

Retriever - Labrador 41
Crossbred Canine/dog 33
Domestic Shorthair 18
Retriever - Golden 15
Shih Tzu 11
Domestic (unspecified) 10
Beagle 10
Terrier - Yorkshire 8
Boxer (German Boxer) 8
Bichon Frise 7

Associated Drugs

Trilostane 55
Oclacitinib Maleate 53
Carprofen 31
Deracoxib 22
Milbemycin Oxime + Spinosad 16
Maropitant Citrate 14
Afoxolaner 14
Moxidectin 13
Insulin Injectable Vial 13
Meloxicam 12
Enrofloxacin 12
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 11
Firocoxib 10
Cyclosporine 9
Cefovecin 9
Selamectin 8
Famotidine 8
Tramadol 8
Fluralaner Chew Tablets 8
Ivermectin + Pyrantel As Pamoate Salt 7

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for MICROORGANISMS, URINE, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (325 here).

Similar death-coded share

Nearest other reactions by death-coded share (20.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for MICROORGANISMS, URINE (#838 of 2,481 by report volume); death-coded 20.6%. PlainBreed reaction plate · death-coded report count stamp 67 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →