MICROORGANISMS, URINE

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VeDDRA Code: 99284

321 adverse event reports referencing this reaction

321
Total Reports
66
Deaths
2060.0%
Death Rate

Species Most Affected

Dog 279
Cat 40
Horse 1
Squirrel 1

Breeds Most Affected

Retriever - Labrador 39
Crossbred Canine/dog 33
Domestic Shorthair 17
Retriever - Golden 15
Shih Tzu 11
Domestic (unspecified) 10
Beagle 10
Terrier - Yorkshire 8
Boxer (German Boxer) 8
Bichon Frise 7

Associated Drugs

Trilostane 54
Oclacitinib Maleate 52
Carprofen 31
Deracoxib 22
Milbemycin Oxime + Spinosad 16
Maropitant Citrate 14
Afoxolaner 14
Moxidectin 13
Insulin Injectable Vial 13
Meloxicam 12
Enrofloxacin 12
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 11
Firocoxib 10
Cyclosporine 9
Cefovecin 9
Selamectin 8
Famotidine 8
Tramadol 8
Fluralaner Chew Tablets 8
Ivermectin + Pyrantel As Pamoate Salt 7

Data Summary

Metric Value
Total reports referencing reaction 321
Reports with fatal outcome 66
Case-fatality rate (reported events) 2060.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99284.

MICROORGANISMS, URINE Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 321 adverse event reports that reference MICROORGANISMS, URINE as a reaction term, including 66 reports with a death outcome — a 2060.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99284, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

MICROORGANISMS, URINE appears most frequently in reports for Dog (279 reports), Cat (40 reports), Horse (1 reports) — with Dog dominating at 279 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (39), Crossbred Canine/dog (33), Domestic Shorthair (17). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with MICROORGANISMS, URINE are Trilostane (54 reports), Oclacitinib Maleate (52 reports), Carprofen (31 reports), Deracoxib (22 reports), with Trilostane appearing alongside this reaction in 54 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial