Swollen gland

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VeDDRA Code: 1814

23 adverse event reports referencing this reaction

23
Total Reports
2
Deaths
870.0%
Death Rate

Species Most Affected

Dog 17
Human 3
Horse 2
Cattle 1

Breeds Most Affected

Unknown 3
Pit Bull 2
Terrier - Yorkshire 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Mixed (Dog) 1
Sheepdog - Shetland 1
Shepherd Dog - Belgian Malinois 1
Collie - Rough-haired 1
Collie - Border 1
Terrier - Bull - American Pit 1

Associated Drugs

Milbemycin Oxime + Spinosad 6
Maropitant Citrate 3
Selamectin 2
Cyclosporine A 2
Gentamicin Sulfate 1
Fipronil 1
Ivermectin 1
Nitenpyram 1
Estriol Tablets 1
Cefovecin 1
Oclacitinib Maleate 1
Emodepside + Praziquantel 1
Flunixin Meglumine Injectable 1
Eiv*3/W,Eev/Ehv1,4/Tet/Yf-Wnv 1
Altrenogest Oily Solution 1
Fluralaner Chew Tablets 1
Canine Influenza Virus H3N8;Canine Influenza Virus H3N2 1
Diphenhydramine Hcl 1
Metronidazole 1
Clindamycin 1

Data Summary

Metric Value
Total reports referencing reaction 23
Reports with fatal outcome 2
Case-fatality rate (reported events) 870.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1814.

Swollen gland Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 23 adverse event reports that reference Swollen gland as a reaction term, including 2 reports with a death outcome — a 870.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1814, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Swollen gland appears most frequently in reports for Dog (17 reports), Human (3 reports), Horse (2 reports) — with Dog dominating at 17 entries. Within those species, the breeds most often named alongside this reaction are Unknown (3), Pit Bull (2), Terrier - Yorkshire (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Swollen gland are Milbemycin Oxime + Spinosad (6 reports), Maropitant Citrate (3 reports), Selamectin (2 reports), Cyclosporine A (2 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 6 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial