Reaction profile

The FDA adverse-event record for dyspnoea

3,279 FDA reports name dyspnoea, a high-volume reaction in the CVM extract (VeDDRA 839). Plate stamps and neighbourhood peers follow.

#141 of 2,481
by report volume (all reactions)
3,279
reports citing this reaction
43.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Dyspnoea has 3,279 reports now versus 3,257 in that prior snapshot: 22 more (0.7%).

Report change
+22
Death-coded reports
+10
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Dyspnoea changes

FDA AER · VeDDRA plate

Code 839 VOL-MID

VOL-MID · DEATH-HOT · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 3,279 reports
  • DEATH-HOT 43.5%
  • TOP-DECILE #141/2481
  • PHOTO-FINISH Difficulty of Use
  • SPECIES-DOG Dog · 2,211
  • DRUG-LEAD Moxidectin · 315
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Difficulty of Use (±7 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Dyspnoea

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Drug dose administrat… · near3322Dyspnoea · this reaction3279Difficulty of Use · near3272Appetite loss · near3271Partial lack of effic… · near3270Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Dyspnoea

Dyspnoea: high death-coded share in the FDA AER plate

Signature read: 1,428 death-coded reports is a heavy tail count for Dyspnoea in the CVM extract. Report volume is upper-third scale: 3,279 named reports in the openFDA extract. Death-coded share is upper-third: 1,428 of 3,279 reports (43.5% of named reports). Nearest volume peer: Difficulty of Use (±7 reports). Lead species Dog (2,211). Lead co-reported drug Moxidectin (315).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,211
Cat 760
Cattle 142
Horse 62
Human 29
Pig 28
Other 20
Goat 7
Sheep 4
Donkey 3

Breeds Most Affected

Domestic Shorthair 302
Domestic (unspecified) 241
Crossbred Canine/dog 204
Retriever - Labrador 200
Chihuahua 109
Terrier - Yorkshire 98
Boxer (German Boxer) 84
Unknown 75
Dog (unknown) 68
Shih Tzu 68

Associated Drugs

Moxidectin 315
Carprofen 204
Maropitant Citrate 187
Cefovecin 159
Selamectin 120
Melarsomine Dihydrochloride 118
Imidacloprid + Moxidectin 112
Cefovecin Sodium 111
Afoxolaner 99
Milbemycin Oxime + Spinosad 95
Oclacitinib Maleate 95
Meloxicam 91
Spinosad 91
Isoflurane 85
Furosemide 80
Pimobendan 78
Prednisone 73
Butorphanol 71
Melarsomine Dihydrochloride Injection 69
Dexamethasone 67

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Dyspnoea, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (43.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Dyspnoea (#141 of 2,481 by report volume); death-coded 43.5%. PlainBreed reaction plate · death-coded report count stamp 1,428 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →