Dyspnoea

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VeDDRA Code: 839

3,225 adverse event reports referencing this reaction

3,225
Total Reports
1,409
Deaths
4370.0%
Death Rate

Species Most Affected

Dog 2,172
Cat 749
Cattle 140
Horse 62
Human 28
Pig 27
Other 20
Goat 7
Sheep 4
Donkey 3

Breeds Most Affected

Domestic Shorthair 293
Domestic (unspecified) 241
Crossbred Canine/dog 201
Retriever - Labrador 196
Chihuahua 109
Terrier - Yorkshire 97
Boxer (German Boxer) 83
Unknown 73
Dog (unknown) 68
Shepherd Dog - German 66

Associated Drugs

Moxidectin 307
Carprofen 200
Maropitant Citrate 171
Cefovecin 156
Selamectin 120
Melarsomine Dihydrochloride 116
Imidacloprid + Moxidectin 112
Cefovecin Sodium 111
Afoxolaner 99
Milbemycin Oxime + Spinosad 95
Oclacitinib Maleate 92
Spinosad 91
Meloxicam 90
Isoflurane 78
Furosemide 76
Pimobendan 74
Prednisone 70
Melarsomine Dihydrochloride Injection 69
Butorphanol 68
Dexamethasone 67

Data Summary

Metric Value
Total reports referencing reaction 3,225
Reports with fatal outcome 1,409
Case-fatality rate (reported events) 4370.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 839.

Dyspnoea Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 3,225 adverse event reports that reference Dyspnoea as a reaction term, including 1,409 reports with a death outcome — a 4370.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 839, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Dyspnoea appears most frequently in reports for Dog (2,172 reports), Cat (749 reports), Cattle (140 reports) — with Dog dominating at 2,172 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (293), Domestic (unspecified) (241), Crossbred Canine/dog (201). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Dyspnoea are Moxidectin (307 reports), Carprofen (200 reports), Maropitant Citrate (171 reports), Cefovecin (156 reports), with Moxidectin appearing alongside this reaction in 307 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial