Reaction profile

The FDA adverse-event record for laminitis

132 FDA adverse-event reports reference laminitis (VeDDRA 617). See the species, breeds, and drugs most associated with it below.

132
reports citing this reaction
23.5%
death-coded share
Horse
most-affected species
Pergolide Mesylate
most-associated drug
Verify with FDA CVM →
132
Total Reports
31
Deaths
23.5%
Death Rate

Species Most Affected

Horse 118
Cattle 10
Dog 1
Mule 1
Donkey 1
Pig 1

Breeds Most Affected

Quarter Horse 27
Horse (unknown) 21
Arab 9
Thoroughbred 8
Pony (unspecified) 8
Horse (other) 6
Tennessee Walking Horse 4
Cattle (unknown) 4
Crossbred Equine/horse 4
Paint 4

Associated Drugs

Pergolide Mesylate 50
Ceftiofur Crystalline Free Acid 17
Triamcinolone Acetonide 8
Ceftiofur 6
Polysulfated Glycosaminoglycan 6
Firocoxib 6
Hyaluronate Sodium 4
Clodronate Disodium 4
Monensin Sodium 3
Omeprazole 3
Phenylbutazone 3
Dexamethasone 3
Tylosin Phosphate 2
Flunixin Meglumine 2
Detomidine Hydrochloride 2
Amikacin 2
Moxidectin 2
West Nile Virus 2
Equine Potomavac - 2639.00 2
Flunixin Meglumine Injectable 2

Laminitis Reaction Insights

132 reports name Laminitis; 31 recorded a death outcome (23.5% of reported events, not a population-level mortality rate). VeDDRA code: 617.

By species: Horse (118 reports), Cattle (10 reports), Dog (1 reports). By breed: Quarter Horse (27), Horse (unknown) (21), Arab (9).

Most co-reported drugs: Pergolide Mesylate (50 reports), Ceftiofur Crystalline Free Acid (17 reports), Triamcinolone Acetonide (8 reports), Ceftiofur (6 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.