Thoracic cavity disorder NOS

Verify with FDA CVM →

VeDDRA Code: 2372

73 adverse event reports referencing this reaction

73
Total Reports
38
Deaths
5210.0%
Death Rate

Species Most Affected

Dog 56
Cat 14
Human 1
Cattle 1
Horse 1

Breeds Most Affected

Domestic Shorthair 12
Retriever - Labrador 6
Shepherd Dog - German 5
Crossbred Canine/dog 4
Shih Tzu 3
Retriever - Golden 3
Beagle 3
Rottweiler 2
Maltese 2
Chihuahua 2

Associated Drugs

Maropitant Citrate 10
Cefovecin 6
Fluralaner Chew Tablets 6
Bedinvetmab 6
Oclacitinib Maleate 5
Milbemycin Oxime + Spinosad 5
Prednisone 5
Doxycycline 5
Pantoprazole 5
Firocoxib 4
Melarsomine Dihydrochloride 4
Famotidine 3
Amoxicillin (As Trihydrate); Clavulanate Potassium ( K-Clavulanate) 3
Metronidazole 3
Enrofloxacin 3
Dexamethasone 3
Insulin Injectable Vial 3
Ivermectin + Pyrantel As Pamoate Salt 3
Propofol 3
Carprofen 3

Data Summary

Metric Value
Total reports referencing reaction 73
Reports with fatal outcome 38
Case-fatality rate (reported events) 5210.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2372.

Thoracic cavity disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 73 adverse event reports that reference Thoracic cavity disorder NOS as a reaction term, including 38 reports with a death outcome — a 5210.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2372, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Thoracic cavity disorder NOS appears most frequently in reports for Dog (56 reports), Cat (14 reports), Human (1 reports) — with Dog dominating at 56 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (12), Retriever - Labrador (6), Shepherd Dog - German (5). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Thoracic cavity disorder NOS are Maropitant Citrate (10 reports), Cefovecin (6 reports), Fluralaner Chew Tablets (6 reports), Bedinvetmab (6 reports), with Maropitant Citrate appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial