Reaction profile

The FDA adverse-event record for pr-injection site, lesion(s)

104 FDA adverse-event reports reference pr-injection site, lesion(s) (VeDDRA 99622). See the species, breeds, and drugs most associated with it below.

104
reports citing this reaction
49.0%
death-coded share
Cat
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
104
Total Reports
51
Deaths
49.0%
Death Rate

Species Most Affected

Cat 53
Dog 30
Horse 10
Cattle 9
Pig 1
Human 1

Breeds Most Affected

Domestic (unspecified) 34
Domestic Shorthair 10
Dachshund (unspecified) 5
Quarter Horse 4
Holstein-Friesian also known as Holstein 3
Siamese 2
Thoroughbred 2
Shepherd Dog - German 2
Terrier - Boston 2
Sheepdog - Shetland 1

Associated Drugs

Robenacoxib 31
Cefovecin 12
Carprofen 9
Cefovecin Sodium 8
Ceftiofur Crystalline Free Acid 8
Lufenuron 6
Ceftiofur 6
Maropitant Citrate 5
Moxidectin 5
Maropitant 3
Polysulfated Glycosaminoglycan 3
Dexmedetomidine Hydrochloride 3
Butorphanol 3
Methylprednisolone Acetate 3
Tramadol 3
Butorphanol Tartrate 2
Enrofloxacin 2
Ceftiofur Hydrochloride 2
Anesthetic 2
Isoflurane 2

PR-INJECTION SITE, LESION(S) Reaction Insights

104 reports name PR-INJECTION SITE, LESION(S); 51 recorded a death outcome (49.0% of reported events, not a population-level mortality rate). VeDDRA code: 99622.

By species: Cat (53 reports), Dog (30 reports), Horse (10 reports). By breed: Domestic (unspecified) (34), Domestic Shorthair (10), Dachshund (unspecified) (5).

Most co-reported drugs: Robenacoxib (31 reports), Cefovecin (12 reports), Carprofen (9 reports), Cefovecin Sodium (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.