Reaction profile

The FDA adverse-event record for pr-injection site, lesion(s)

106 FDA adverse-event reports reference pr-injection site, lesion(s) (VeDDRA 99622). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1365 of 2,481
by report volume (all reactions)
106
reports citing this reaction
48.1%
death-coded share
Cat
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-INJECTION SITE, LESION(S) has 106 reports now versus 104 in that prior snapshot: 2 more (1.9%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-INJECTION SITE, LESION(S) changes

FDA AER · VeDDRA plate

Code 99622 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 106 reports
  • DEATH-HOT 48.1%
  • MID-PACK #1365/2481
  • PHOTO-FINISH Contamination, Insects
  • SPECIES-CAT Cat · 53
  • DRUG-LEAD Robenacoxib · 31
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Contamination, Insects (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around PR-INJECTION SITE, LESION

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Contamination, Insects · near106Gall bladder inflamma… · near106Injection site pannic… · near106Painful defecation · near106PR-INJECTION SITE, LE… · thi…106Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around PR-INJECTION SITE, LESION(S)

PR-INJECTION SITE, LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-INJECTION SITE, LESION(S)'s 48.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 51 of 106 reports (48.1% of named reports). Nearest volume peer: Contamination, Insects (±0 reports). Lead species Cat (53). Lead co-reported drug Robenacoxib (31).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 53
Dog 32
Horse 10
Cattle 9
Pig 1
Human 1

Breeds Most Affected

Domestic (unspecified) 34
Domestic Shorthair 10
Dachshund (unspecified) 5
Quarter Horse 4
Holstein-Friesian also known as Holstein 3
Siamese 2
Thoroughbred 2
Shepherd Dog - Australian 2
Shepherd Dog - German 2
Terrier - Boston 2

Associated Drugs

Robenacoxib 31
Cefovecin 12
Carprofen 9
Cefovecin Sodium 8
Ceftiofur Crystalline Free Acid 8
Moxidectin 7
Lufenuron 6
Ceftiofur 6
Maropitant Citrate 5
Maropitant 3
Polysulfated Glycosaminoglycan 3
Dexmedetomidine Hydrochloride 3
Butorphanol 3
Methylprednisolone Acetate 3
Tramadol 3
Butorphanol Tartrate 2
Enrofloxacin 2
Ceftiofur Hydrochloride 2
Anesthetic 2
Isoflurane 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for PR-INJECTION SITE, LESION(S), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (48.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-INJECTION SITE, LESION(S) (#1365 of 2,481 by report volume); death-coded 48.1%. PlainBreed reaction plate · death-coded share stamp 48.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →