Reaction profile

The FDA adverse-event record for lip disorder nos

156 FDA adverse-event reports reference lip disorder nos (VeDDRA 2446). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1164 of 2,481
by report volume (all reactions)
156
reports citing this reaction
9.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lip disorder NOS has 156 reports now versus 154 in that prior snapshot: 2 more (1.3%).

Report change
+2
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lip disorder NOS changes

FDA AER · VeDDRA plate

Code 2446 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 156 reports
  • DEATH-PAR 9.6%
  • MID-PACK #1164/2481
  • PHOTO-FINISH Abnormal necropsy fin…
  • SPECIES-DOG Dog · 103
  • DRUG-LEAD Oclacitinib Malea… · 20
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal necropsy finding (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lip disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal necropsy fin… · near156Delayed healing · near156Lip disorder NOS · this reac…156Retinal degeneration · near156Swollen joint · near156Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lip disorder NOS

What the FDA AER plate says about Lip disorder NOS

Signature read: death-coded share at 9.6% is the most distinctive outcome stamp on Lip disorder NOS. Report volume sits in the middle third of the reaction corpus. 15 of 156 reports were death-coded (9.6% of named reports, not a population mortality rate). Nearest volume peer: Abnormal necropsy finding (±0 reports). Lead species Dog (103). Lead co-reported drug Oclacitinib Maleate (20).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 103
Horse 23
Human 16
Cat 14

Breeds Most Affected

Unknown 16
Crossbred Canine/dog 14
Retriever - Labrador 14
Domestic Shorthair 10
Horse (unknown) 7
Quarter Horse 7
Dog (unknown) 6
Terrier - Yorkshire 5
Chihuahua 5
Shepherd Dog - German 5

Associated Drugs

Oclacitinib Maleate 20
Maropitant Citrate 16
Carprofen 14
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 12
Cefovecin 12
Afoxolaner 11
Prednisone 11
Fluralaner Chew Tablets 9
Omeprazole 8
Selamectin 8
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 8
Ivermectin 7
Fluralaner 13.64% 12-Week Chew 6
Bedinvetmab 6
Meloxicam 5
Dexmedetomidine Hydrochloride 5
Dexamethasone 5
Anti-Il31 Mab Mcs Lot #1283563 5
Gabapentin 5
Fish Oil 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lip disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (156 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lip disorder NOS (#1164 of 2,481 by report volume); death-coded 9.6%. PlainBreed reaction plate · death-coded share stamp 9.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →