Reaction profile

The FDA adverse-event record for lip disorder nos

152 FDA adverse-event reports reference lip disorder nos (VeDDRA 2446). See the species, breeds, and drugs most associated with it below.

152
reports citing this reaction
9.9%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
152
Total Reports
15
Deaths
9.9%
Death Rate

Species Most Affected

Dog 99
Horse 23
Human 16
Cat 14

Breeds Most Affected

Unknown 16
Crossbred Canine/dog 14
Retriever - Labrador 13
Domestic Shorthair 10
Horse (unknown) 7
Quarter Horse 7
Dog (unknown) 6
Terrier - Yorkshire 5
Chihuahua 5
Shepherd Dog - German 5

Associated Drugs

Oclacitinib Maleate 20
Maropitant Citrate 15
Carprofen 14
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 12
Cefovecin 12
Afoxolaner 10
Prednisone 10
Fluralaner Chew Tablets 9
Omeprazole 8
Selamectin 8
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 8
Ivermectin 7
Fluralaner 13.64% 12-Week Chew 6
Bedinvetmab 6
Meloxicam 5
Dexmedetomidine Hydrochloride 5
Dexamethasone 5
Anti-Il31 Mab Mcs Lot #1283563 5
Gabapentin 5
Fish Oil 5

Lip disorder NOS Reaction Insights

152 reports name Lip disorder NOS; 15 recorded a death outcome (9.9% of reported events, not a population-level mortality rate). VeDDRA code: 2446.

By species: Dog (99 reports), Horse (23 reports), Human (16 reports). By breed: Unknown (16), Crossbred Canine/dog (14), Retriever - Labrador (13).

Most co-reported drugs: Oclacitinib Maleate (20 reports), Maropitant Citrate (15 reports), Carprofen (14 reports), Ivermectin(1.55%)/Praziquantel(7.75%) Paste (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.