Cardiac enlargement
VeDDRA Code: 204
1,100 adverse event reports referencing this reaction
1,100
Total Reports
432
Deaths
3930.0%
Death Rate
Species Most Affected
Dog 868
Cat 195
Cattle 26
Other Birds 3
Pig 3
Sheep 2
Other Canids 1
Human 1
Horse 1
Breeds Most Affected
Domestic Shorthair 88
Chihuahua 84
Retriever - Labrador 63
Terrier - Yorkshire 53
Crossbred Canine/dog 48
Dachshund (unspecified) 35
Domestic (unspecified) 34
Shih Tzu 34
Maltese 30
Beagle 27
Associated Drugs
Milbemycin Oxime + Spinosad 166
Bedinvetmab 76
Maropitant Citrate 73
Trilostane 63
Pimobendan 59
Furosemide 53
Moxidectin 52
Cefovecin 52
Spinosad 50
Prednisone 49
Oclacitinib Maleate 49
Gabapentin 43
Ivermectin + Pyrantel As Pamoate Salt 42
Carprofen 40
Afoxolaner 38
Selamectin 36
Doxycycline 34
Milbemycin Oxime + Praziquantel 33
Fluralaner Chew Tablets 30
Imidacloprid + Moxidectin 28
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.