Reaction profile

The FDA adverse-event record for epidermal collarette

185 FDA adverse-event reports reference epidermal collarette (VeDDRA 2263). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1077 of 2,481
by report volume (all reactions)
185
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Epidermal collarette has 185 reports now versus 185 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Epidermal collarette changes

FDA AER · VeDDRA plate

Code 2263 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 185 reports
  • DEATH-LOW 4.3%
  • MID-PACK #1077/2481
  • PHOTO-FINISH Coughing up blood
  • SPECIES-DOG Dog · 174
  • DRUG-LEAD Oclacitinib Malea… · 38
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Coughing up blood (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Epidermal collarette

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Coughing up blood · near185Epidermal collarette · this …185Peripheral nervous sy… · near185Thyroid gland disorde… · near185BANDS(NEUTROPHILS) HI… · near184Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Epidermal collarette

Epidermal collarette: low death-coded share in the FDA AER plate

Signature read: Epidermal collarette's 4.3% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 8 of 185 reports (4.3% of named reports). Nearest volume peer: Coughing up blood (±0 reports). Lead species Dog (174). Lead co-reported drug Oclacitinib Maleate (38).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 174
Cat 11

Breeds Most Affected

Retriever - Golden 14
Retriever - Labrador 14
Crossbred Canine/dog 11
Domestic Shorthair 8
Terrier (unspecified) 8
Terrier - Bull - American Pit 8
Terrier - Boston 7
Shih Tzu 6
Pinscher - Miniature 5
Terrier - Yorkshire 5

Associated Drugs

Oclacitinib Maleate 38
Trilostane 29
Anti-Il31 Mab Mcs Lot #1283563 27
Bedinvetmab 23
Afoxolaner 16
Prednisone 16
Milbemycin Oxime + Spinosad 15
Gabapentin 14
Fluralaner Chew Tablets 13
Carprofen 13
Cefpodoxime Proxetil 12
Cefpodoxime 10
Moxidectin 8
Maropitant Citrate 7
Cephalexin 7
Cefovecin 6
Cyclosporine 6
Ketoconazole 6
Fluid Therapy 6
Ivermectin + Pyrantel As Pamoate Salt 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Epidermal collarette, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (4.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Epidermal collarette (#1077 of 2,481 by report volume); death-coded 4.3%. PlainBreed reaction plate · death-coded share stamp 4.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →