Reaction profile

The FDA adverse-event record for epidermal collarette

177 FDA adverse-event reports reference epidermal collarette (VeDDRA 2263). See the species, breeds, and drugs most associated with it below.

177
reports citing this reaction
3.4%
death-coded share
Dog
most-affected species
Oclacitinib Maleate
most-associated drug
Verify with FDA CVM →
177
Total Reports
6
Deaths
3.4%
Death Rate

Species Most Affected

Dog 166
Cat 11

Breeds Most Affected

Retriever - Golden 14
Retriever - Labrador 12
Crossbred Canine/dog 11
Domestic Shorthair 8
Terrier - Bull - American Pit 8
Terrier - Boston 7
Shih Tzu 6
Terrier (unspecified) 6
Terrier - Yorkshire 5
Pinscher - Miniature 5

Associated Drugs

Oclacitinib Maleate 32
Trilostane 29
Anti-Il31 Mab Mcs Lot #1283563 23
Bedinvetmab 22
Afoxolaner 16
Milbemycin Oxime + Spinosad 15
Fluralaner Chew Tablets 13
Prednisone 13
Gabapentin 13
Cefpodoxime Proxetil 12
Carprofen 11
Moxidectin 8
Cefpodoxime 7
Cephalexin 7
Cefovecin 6
Cyclosporine 6
Maropitant Citrate 6
Ivermectin + Pyrantel As Pamoate Salt 5
Levothyroxine 5
Pyrantel Pamoate;Sarolaner 5

Epidermal collarette Reaction Insights

177 reports name Epidermal collarette; 6 recorded a death outcome (3.4% of reported events, not a population-level mortality rate). VeDDRA code: 2263.

By species: Dog (166 reports), Cat (11 reports). By breed: Retriever - Golden (14), Retriever - Labrador (12), Crossbred Canine/dog (11).

Most co-reported drugs: Oclacitinib Maleate (32 reports), Trilostane (29 reports), Anti-Il31 Mab Mcs Lot #1283563 (23 reports), Bedinvetmab (22 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.