Reaction profile

The FDA adverse-event record for polyarthritis

77 FDA adverse-event reports reference polyarthritis (VeDDRA 574). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1522 of 2,481
by report volume (all reactions)
77
reports citing this reaction
19.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Polyarthritis has 77 reports now versus 77 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Polyarthritis changes

FDA AER · VeDDRA plate

Code 574 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 77 reports
  • DEATH-ELEV 19.5%
  • MID-PACK #1522/2481
  • PHOTO-FINISH Application site twit…
  • SPECIES-DOG Dog · 69
  • DRUG-LEAD Carprofen · 13
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site twitching (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Polyarthritis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site twit… · near77Cutaneous oedema · near77Dermal plaque · near77Drug preparation error · near77Polyarthritis · this reaction77Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Polyarthritis

What the FDA AER plate says about Polyarthritis

Signature read: report volume at 77 (#1522 of 2,481) is the standout scale stamp on Polyarthritis. Report volume sits in the middle third of the reaction corpus. 15 of 77 reports were death-coded (19.5% of named reports, not a population mortality rate). Nearest volume peer: Application site twitching (±0 reports). Lead species Dog (69). Lead co-reported drug Carprofen (13).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 69
Cat 4
Cattle 3
Human 1

Breeds Most Affected

Retriever - Labrador 13
Boxer (German Boxer) 4
Retriever - Golden 4
Shepherd Dog - German 4
Dog (unknown) 3
Collie - Border 3
Spaniel - Cocker American 3
Crossbred Canine/dog 2
Domestic Mediumhair 2
Pointing Dog - Hungarian Short-haired (Vizsla) 2

Associated Drugs

Carprofen 13
Tramadol 10
Milbemycin Oxime + Spinosad 9
Prednisone 9
Bedinvetmab 9
Maropitant Citrate 8
Doxycycline 8
Oclacitinib Maleate 7
Gabapentin 6
Afoxolaner 6
Deracoxib 5
Polysulfated Glycosaminoglycan 5
Fluralaner Chew Tablets 5
Omeprazole 4
Antibiotic 4
Ivermectin + Pyrantel As Pamoate Salt 4
Meloxicam 4
Metronidazole 3
Grapiprant 3
Lotilaner 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Polyarthritis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (77 here).

Similar death-coded share

Nearest other reactions by death-coded share (19.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Polyarthritis (#1522 of 2,481 by report volume); death-coded 19.5%. PlainBreed reaction plate · report volume stamp 77 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →