Reaction profile

The FDA adverse-event record for leukopenia nos

161 FDA adverse-event reports reference leukopenia nos (VeDDRA 164). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1150 of 2,481
by report volume (all reactions)
161
reports citing this reaction
14.9%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Leukopenia NOS has 161 reports now versus 43 in that prior snapshot: 118 more (274.4%).

Report change
+118
Death-coded reports
+19
Death-coded share
+3.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Leukopenia NOS changes

FDA AER · VeDDRA plate

Code 164 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 161 reports
  • DEATH-ELEV 14.9%
  • MID-PACK #1150/2481
  • PHOTO-FINISH Increased lung sounds
  • SPECIES-DOG Dog · 143
  • DRUG-LEAD Ilunocitinib · 76
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Increased lung sounds (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Leukopenia NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Increased lung sounds · near161Lack of efficacy · near161Leukopenia NOS · this reacti…161Muscle pain · near161Belching · near160Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Leukopenia NOS

What the FDA AER plate says about Leukopenia NOS

Signature read: 24 death-coded reports is the most distinctive absolute-outcome stamp on Leukopenia NOS. Report volume sits in the middle third of the reaction corpus. 24 of 161 reports were death-coded (14.9% of named reports, not a population mortality rate). Nearest volume peer: Increased lung sounds (±0 reports). Lead species Dog (143). Lead co-reported drug Ilunocitinib (76).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ilunocitinib appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 143
Cat 15
Horse 3

Breeds Most Affected

Retriever - Labrador 29
Pit Bull 11
Domestic Shorthair 10
Crossbred Canine/dog 9
Retriever - Golden 8
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 6
Bulldog - French 5
Chihuahua 5
Bulldog - English 4
Terrier - West Highland White 4

Associated Drugs

Ilunocitinib 76
Oclacitinib Maleate 51
Maropitant Citrate 28
Ketoconazole 13
Gabapentin 10
Bedinvetmab 10
Immunotherapy 10
Metronidazole 10
Diphenhydramine 9
Afoxolaner 9
Buprenorphine 8
Lotilaner 7
Pyrantel Pamoate;Sarolaner 7
Anti-Il31 Mab Mcs Lot #1283563 7
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 7
Doxycycline 6
Trazodone 6
Fluralaner 6
Leptospirosis Vaccine 6
Carprofen 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Leukopenia NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (161 here).

Similar death-coded share

Nearest other reactions by death-coded share (14.9% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Leukopenia NOS (#1150 of 2,481 by report volume); death-coded 14.9%. PlainBreed reaction plate · death-coded report count stamp 24 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →