Reaction profile

The FDA adverse-event record for metritis

Name: Metritis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

26 FDA reports name metritis, a lower-volume reaction in the CVM extract (VeDDRA 807). Plate stamps and neighbourhood peers follow.

#2059 of 2,481
by report volume (all reactions): 26
reports citing this reaction: 34.6%
death-coded share: Cattle
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Metritis has 26 reports now versus 26 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Metritis changes

FDA AER · VeDDRA plate

Code 807 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CATTLE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 26 reports
DEATH-HOT 34.6%
LOWER-Q #2059/2481
PHOTO-FINISH Cushings disease - pi…
SPECIES-CATTLE Cattle · 21
DRUG-LEAD Pegbovigrastim · 10
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Cushings disease - pituitary dependent (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Metritis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Metritis

Metritis: high death-coded share in the FDA AER plate

Signature read: 26 reports place Metritis in the lower third of FDA AER volume (#2059 of 2,481). Report volume is lower-third scale: 26 named reports in the openFDA extract. Death-coded share is upper-third: 9 of 26 reports (34.6% of named reports). Nearest volume peer: Cushings disease - pituitary dependent (±0 reports). Lead species Cattle (21). Lead co-reported drug Pegbovigrastim (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cattle 21

Dog 3

Goat 1

Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 15

Cattle (other) 3

Mixed (Cattle) 1

Boer 1

Shorthorn - Milking 1

Cattle (unknown) 1

Bichon Frise 1

Siberian Husky 1

Shepherd Dog - Australian 1

Arab 1

Associated Drugs

Pegbovigrastim 10

Monensin Sodium 7

Cloxacillin Benz Intramam Dc 2

Monensin 1

Eprinomectin 1

Sometribove 1

Ceftiofur Crystalline Free Acid 1

Progesterone 1

Flunixin Meglumine 1

Afoxolaner 1

Ivermectin + Pyrantel As Pamoate Salt 1

Cefovecin 1

Ampicillin Trihydrate 1

Sodium Chloride 1

Peg-Bfgf-21 1

Ceftiofur Sodium 1

Bismuth Subnitr Intramammary 1

Bismuth Subnitrate 1

Domperidone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Metritis (#2059 of 2,481 by report volume); death-coded 34.6%. PlainBreed reaction plate · report volume stamp 26 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →