Metritis

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VeDDRA Code: 807

26 adverse event reports referencing this reaction

26
Total Reports
9
Deaths
3460.0%
Death Rate

Species Most Affected

Cattle 21
Dog 3
Goat 1
Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 15
Cattle (other) 3
Mixed (Cattle) 1
Boer 1
Shorthorn - Milking 1
Cattle (unknown) 1
Bichon Frise 1
Siberian Husky 1
Shepherd Dog - Australian 1
Arab 1

Associated Drugs

Pegbovigrastim 10
Monensin Sodium 7
Cloxacillin Benz Intramam Dc 2
Monensin 1
Eprinomectin 1
Sometribove 1
Ceftiofur Crystalline Free Acid 1
Progesterone 1
Flunixin Meglumine 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Ampicillin Trihydrate 1
Cefovecin 1
Sodium Chloride 1
Peg-Bfgf-21 1
Ceftiofur Sodium 1
Bismuth Subnitr Intramammary 1
Bismuth Subnitrate 1
Domperidone 1

Data Summary

Metric Value
Total reports referencing reaction 26
Reports with fatal outcome 9
Case-fatality rate (reported events) 3460.0%
Species observed 4
Breeds observed 10
Drugs associated with reaction 19

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 807.

Metritis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 26 adverse event reports that reference Metritis as a reaction term, including 9 reports with a death outcome — a 3460.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 807, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Metritis appears most frequently in reports for Cattle (21 reports), Dog (3 reports), Goat (1 reports) — with Cattle dominating at 21 entries. Within those species, the breeds most often named alongside this reaction are Holstein-Friesian also known as Holstein (15), Cattle (other) (3), Mixed (Cattle) (1). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Metritis are Pegbovigrastim (10 reports), Monensin Sodium (7 reports), Cloxacillin Benz Intramam Dc (2 reports), Monensin (1 reports), with Pegbovigrastim appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial