Reaction profile

The FDA adverse-event record for metritis

26 FDA adverse-event reports reference metritis (VeDDRA 807). See the species, breeds, and drugs most associated with it below.

26
reports citing this reaction
34.6%
death-coded share
Cattle
most-affected species
Pegbovigrastim
most-associated drug
Verify with FDA CVM →
26
Total Reports
9
Deaths
34.6%
Death Rate

Species Most Affected

Cattle 21
Dog 3
Goat 1
Horse 1

Breeds Most Affected

Holstein-Friesian also known as Holstein 15
Cattle (other) 3
Mixed (Cattle) 1
Boer 1
Shorthorn - Milking 1
Cattle (unknown) 1
Bichon Frise 1
Siberian Husky 1
Shepherd Dog - Australian 1
Arab 1

Associated Drugs

Pegbovigrastim 10
Monensin Sodium 7
Cloxacillin Benz Intramam Dc 2
Monensin 1
Eprinomectin 1
Sometribove 1
Ceftiofur Crystalline Free Acid 1
Progesterone 1
Flunixin Meglumine 1
Afoxolaner 1
Ivermectin + Pyrantel As Pamoate Salt 1
Ampicillin Trihydrate 1
Cefovecin 1
Sodium Chloride 1
Peg-Bfgf-21 1
Ceftiofur Sodium 1
Bismuth Subnitr Intramammary 1
Bismuth Subnitrate 1
Domperidone 1

Metritis Reaction Insights

26 reports name Metritis; 9 recorded a death outcome (34.6% of reported events, not a population-level mortality rate). VeDDRA code: 807.

By species: Cattle (21 reports), Dog (3 reports), Goat (1 reports). By breed: Holstein-Friesian also known as Holstein (15), Cattle (other) (3), Mixed (Cattle) (1).

Most co-reported drugs: Pegbovigrastim (10 reports), Monensin Sodium (7 reports), Cloxacillin Benz Intramam Dc (2 reports), Monensin (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.