Reaction profile

The FDA adverse-event record for loss of vision

378 FDA adverse-event reports reference loss of vision (VeDDRA 1596). See the species, breeds, and drugs most associated with it below.

378
reports citing this reaction
23.3%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
378
Total Reports
88
Deaths
23.3%
Death Rate

Species Most Affected

Dog 300
Cat 73
Human 3
Horse 2

Breeds Most Affected

Domestic Shorthair 44
Chihuahua 26
Retriever - Labrador 24
Crossbred Canine/dog 19
Terrier - Yorkshire 14
Shepherd Dog - German 12
Dog (unknown) 12
Collie - Border 12
Terrier - Jack Russell 9
Domestic Longhair 9

Associated Drugs

Bedinvetmab 42
Milbemycin Oxime + Spinosad 31
Carprofen 25
Afoxolaner 24
Pyrantel Pamoate;Sarolaner 24
Trilostane 20
Oclacitinib Maleate 19
Maropitant Citrate 16
Ivermectin + Pyrantel As Pamoate Salt 16
Spinosad 14
Cefovecin 13
Enrofloxacin 13
Moxidectin 12
Gabapentin 12
Selamectin 11
Fluralaner Chew Tablets 11
Recombinant Human Insulin 10
Prednisone 10
Frunevetmab 10
Buprenorphine 9

Loss of vision Reaction Insights

378 reports name Loss of vision; 88 recorded a death outcome (23.3% of reported events, not a population-level mortality rate). VeDDRA code: 1596.

By species: Dog (300 reports), Cat (73 reports), Human (3 reports). By breed: Domestic Shorthair (44), Chihuahua (26), Retriever - Labrador (24).

Most co-reported drugs: Bedinvetmab (42 reports), Milbemycin Oxime + Spinosad (31 reports), Carprofen (25 reports), Afoxolaner (24 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.