Reaction profile

The FDA adverse-event record for loss of vision

405 FDA reports name loss of vision, a high-volume reaction in the CVM extract (VeDDRA 1596). Plate stamps and neighbourhood peers follow.

#720 of 2,481
by report volume (all reactions)
405
reports citing this reaction
23.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Loss of vision has 405 reports now versus 393 in that prior snapshot: 12 more (3.1%).

Report change
+12
Death-coded reports
+2
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Loss of vision changes

FDA AER · VeDDRA plate

Code 1596 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 405 reports
  • DEATH-HOT 23.2%
  • MID-PACK #720/2481
  • PHOTO-FINISH Oral ulceration
  • SPECIES-DOG Dog · 320
  • DRUG-LEAD Bedinvetmab · 49
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Oral ulceration (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Loss of vision

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Injection site scab · near406Product defect NOS · near406Loss of vision · this reacti…405Oral ulceration · near405Focal seizure · near404Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Loss of vision

What the FDA AER plate says about Loss of vision

Signature read: 94 death-coded reports is a heavy tail count for Loss of vision in the CVM extract. Report volume is upper-third scale: 405 named reports in the openFDA extract. 94 of 405 reports were death-coded (23.2% of named reports, not a population mortality rate). Nearest volume peer: Oral ulceration (±0 reports). Lead species Dog (320). Lead co-reported drug Bedinvetmab (49).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Bedinvetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 320
Cat 80
Human 3
Horse 2

Breeds Most Affected

Domestic Shorthair 48
Chihuahua 26
Retriever - Labrador 25
Crossbred Canine/dog 20
Shepherd Dog - German 15
Terrier - Yorkshire 14
Dog (unknown) 13
Collie - Border 12
Domestic Longhair 11
Terrier - Jack Russell 9

Associated Drugs

Bedinvetmab 49
Milbemycin Oxime + Spinosad 31
Carprofen 28
Pyrantel Pamoate;Sarolaner 28
Afoxolaner 26
Trilostane 22
Oclacitinib Maleate 19
Maropitant Citrate 16
Ivermectin + Pyrantel As Pamoate Salt 16
Enrofloxacin 15
Spinosad 14
Cefovecin 14
Gabapentin 14
Moxidectin 12
Frunevetmab 12
Selamectin 11
Fluralaner Chew Tablets 11
Prednisone 10
Recombinant Human Insulin 10
Fluralaner 13.64% 12-Week Chew 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Loss of vision, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (405 here).

Similar death-coded share

Nearest other reactions by death-coded share (23.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Loss of vision (#720 of 2,481 by report volume); death-coded 23.2%. PlainBreed reaction plate · death-coded report count stamp 94 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →