Reaction profile

The FDA adverse-event record for wheezing

876 FDA reports name wheezing, a high-volume reaction in the CVM extract (VeDDRA 836). Plate stamps and neighbourhood peers follow.

#434 of 2,481
by report volume (all reactions)
876
reports citing this reaction
17.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Wheezing has 876 reports now versus 865 in that prior snapshot: 11 more (1.3%).

Report change
+11
Death-coded reports
+1
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Wheezing changes

FDA AER · VeDDRA plate

Code 836 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 876 reports
  • DEATH-ELEV 17.2%
  • UPPER-Q #434/2481
  • PHOTO-FINISH Injection site reacti…
  • SPECIES-DOG Dog · 623
  • DRUG-LEAD Milbemycin Oxime… · 98
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Injection site reaction NOS (±1 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Wheezing

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Incoordination · near882Intestinal disorder N… · near881Closure, Missing · near878Wheezing · this reaction876Injection site reacti… · near875Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Wheezing

What the FDA AER plate says about Wheezing

Signature read: 151 death-coded reports is a heavy tail count for Wheezing in the CVM extract. Report volume is upper-third scale: 876 named reports in the openFDA extract. 151 of 876 reports were death-coded (17.2% of named reports, not a population mortality rate). Nearest volume peer: Injection site reaction NOS (±1 reports). Lead species Dog (623). Lead co-reported drug Milbemycin Oxime + Spinosad (98).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 623
Cat 214
Human 15
Horse 11
Cattle 7
Rat 1
Rabbit 1
Other Reptiles 1
Guinea Pig 1
Turtle 1

Breeds Most Affected

Domestic Shorthair 119
Chihuahua 56
Crossbred Canine/dog 55
Terrier - Yorkshire 39
Retriever - Labrador 29
Maltese 26
Shih Tzu 24
Dachshund (unspecified) 22
Unknown 22
Terrier - Jack Russell 19

Associated Drugs

Milbemycin Oxime + Spinosad 98
Maropitant Citrate 58
Moxidectin 49
Carprofen 44
Afoxolaner 37
Selamectin 32
Cefovecin 32
Oclacitinib Maleate 30
Spinosad 26
Imidacloprid + Moxidectin 26
Bedinvetmab 25
Pimobendan 24
Ivermectin + Pyrantel As Pamoate Salt 23
Prednisone 22
Fluralaner Chew Tablets 21
Doxycycline 20
Nitenpyram 20
Frunevetmab 20
Enrofloxacin 19
Furosemide 19

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Wheezing, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (876 here).

Similar death-coded share

Nearest other reactions by death-coded share (17.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Wheezing (#434 of 2,481 by report volume); death-coded 17.2%. PlainBreed reaction plate · death-coded report count stamp 151 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →