Reaction profile

The FDA adverse-event record for oral ulceration

405 FDA reports name oral ulceration, a high-volume reaction in the CVM extract (VeDDRA 301). Plate stamps and neighbourhood peers follow.

#721 of 2,481
by report volume (all reactions)
405
reports citing this reaction
19.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Oral ulceration has 405 reports now versus 401 in that prior snapshot: 4 more (1.0%).

Report change
+4
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Oral ulceration changes

FDA AER · VeDDRA plate

Code 301 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 405 reports
  • DEATH-ELEV 19.3%
  • MID-PACK #721/2481
  • PHOTO-FINISH Loss of vision
  • SPECIES-DOG Dog · 214
  • DRUG-LEAD Carprofen · 29
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Loss of vision (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Oral ulceration

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Injection site scab · near406Product defect NOS · near406Loss of vision · near405Oral ulceration · this react…405Focal seizure · near404Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Oral ulceration

What the FDA AER plate says about Oral ulceration

Signature read: 78 death-coded reports is a heavy tail count for Oral ulceration in the CVM extract. Report volume is upper-third scale: 405 named reports in the openFDA extract. 78 of 405 reports were death-coded (19.3% of named reports, not a population mortality rate). Nearest volume peer: Loss of vision (±0 reports). Lead species Dog (214). Lead co-reported drug Carprofen (29).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 214
Cat 108
Horse 73
Cattle 3
Donkey 3
Human 1
Sheep 1
Pig 1
Ferret 1

Breeds Most Affected

Domestic Shorthair 56
Crossbred Canine/dog 23
Quarter Horse 19
Horse (unknown) 17
Retriever - Labrador 17
Domestic (unspecified) 12
Thoroughbred 10
Cat (unknown) 9
Shepherd Dog - Australian 9
Collie - Border 9

Associated Drugs

Carprofen 29
Meloxicam 28
Maropitant Citrate 27
Cefovecin 26
Firocoxib 22
Gabapentin 22
Ivermectin, Praziquantel 19
Robenacoxib 18
Oclacitinib Maleate 17
Selamectin 15
Ivermectin + Praziquantel 15
Milbemycin Oxime + Spinosad 14
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 14
Prednisone 14
Enrofloxacin 13
Cyclosporine A 13
Buprenorphine 12
Trilostane 12
Cyclosporine 11
Deracoxib 10

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Oral ulceration, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (405 here).

Similar death-coded share

Nearest other reactions by death-coded share (19.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Oral ulceration (#721 of 2,481 by report volume); death-coded 19.3%. PlainBreed reaction plate · death-coded report count stamp 78 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →