Reaction profile

The FDA adverse-event record for blood in faeces

2,312 FDA reports name blood in faeces, a high-volume reaction in the CVM extract (VeDDRA 1081). Plate stamps and neighbourhood peers follow.

#201 of 2,481
by report volume (all reactions)
2,312
reports citing this reaction
11.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Blood in faeces has 2,312 reports now versus 2,283 in that prior snapshot: 29 more (1.3%).

Report change
+29
Death-coded reports
+2
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Blood in faeces changes

FDA AER · VeDDRA plate

Code 1081 VOL-MID

VOL-MID · DEATH-ELEV · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 2,312 reports
  • DEATH-ELEV 11.0%
  • TOP-DECILE #201/2481
  • PHOTO-FINISH Heart murmur
  • SPECIES-DOG Dog · 2,157
  • DRUG-LEAD Milbemycin Oxime… · 228
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Heart murmur (±16 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Blood in faeces

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Rash · near2339Heart murmur · near2328Blood in faeces · this react…2312Muscle tremor · near2279Containers, Abnormal · near2277Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Blood in faeces

What the FDA AER plate says about Blood in faeces

Signature read: 2,312 reports place Blood in faeces in the upper third of FDA AER volume (#201 of 2,481). Report volume is upper-third scale: 2,312 named reports in the openFDA extract. 255 of 2,312 reports were death-coded (11.0% of named reports, not a population mortality rate). Nearest volume peer: Heart murmur (±16 reports). Lead species Dog (2,157). Lead co-reported drug Milbemycin Oxime + Spinosad (228).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 2,157
Cat 117
Cattle 21
Horse 8
Human 5
Chicken 2
Pig 1
Other Rodents 1

Breeds Most Affected

Retriever - Labrador 200
Crossbred Canine/dog 158
Chihuahua 98
Terrier - Yorkshire 91
Retriever - Golden 81
Beagle 75
Domestic Shorthair 73
Shih Tzu 71
Dog (unknown) 69
Dachshund (unspecified) 55

Associated Drugs

Milbemycin Oxime + Spinosad 228
Ivermectin + Pyrantel As Pamoate Salt 214
Carprofen 208
Afoxolaner 122
Maropitant Citrate 118
Fluralaner Chew Tablets 115
Moxidectin 101
Oclacitinib Maleate 95
Grapiprant 95
Metronidazole 62
Pyrantel Pamoate;Sarolaner 60
Spinosad 55
Imidacloprid + Moxidectin 54
Bedinvetmab 54
Milbemycin Oxime + Praziquantel 53
Meloxicam 52
Trilostane 48
Lufenuron + Milbemycin Oxime 47
Milbemycin Oxime, Lufenuron 46
Selamectin 44

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Blood in faeces, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (2,312 here).

Similar death-coded share

Nearest other reactions by death-coded share (11.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Blood in faeces (#201 of 2,481 by report volume); death-coded 11.0%. PlainBreed reaction plate · report volume stamp 2,312 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →