Reaction profile

The FDA adverse-event record for joint ache

Name: Joint ache - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

11 FDA reports name joint ache, a lower-volume reaction in the CVM extract (VeDDRA 587). Plate stamps and neighbourhood peers follow.

#2427 of 2,481
by report volume (all reactions): 11
reports citing this reaction: 9.1%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Joint ache has 11 reports now versus 11 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Joint ache changes

FDA AER · VeDDRA plate

Code 587 VOL-TRACE

VOL-TRACE · DEATH-PAR · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-MID · BOOK-FULL

VOL-TRACE 11 reports
DEATH-PAR 9.1%
BOTTOM-DECILE #2427/2481
PHOTO-FINISH ABNORMAL PANCREATIC S…
SPECIES-DOG Dog · 7
DRUG-LEAD Oclacitinib Malea… · 2
DESK-MID 7 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Joint ache

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Joint ache

What the FDA AER plate says about Joint ache

Signature read: 11 reports place Joint ache in the lower third of FDA AER volume (#2427 of 2,481). Report volume is lower-third scale: 11 named reports in the openFDA extract. 1 of 11 reports were death-coded (9.1% of named reports, not a population mortality rate). Nearest volume peer: ABNORMAL PANCREATIC SPECIFIC LIPASE (PLI) (±0 reports). Lead species Dog (7). Lead co-reported drug Oclacitinib Maleate (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Oclacitinib Maleate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 7

Human 4

Breeds Most Affected

Unknown 4

Retriever - Golden 2

Maltese 1

Boxer (German Boxer) 1

Retriever (unspecified) 1

Pit Bull 1

Rottweiler 1

Associated Drugs

Oclacitinib Maleate 2

Selamectin 1

Tilmicosin Phosphate 1

Estriol Tablets 1

Oxytetracycline Hydrochloride 1

Fluralaner Chew Tablets 1

Moxidectin 1

Pyrantel Pamoate;Sarolaner 1

Sarolaner 1

Afoxolaner 1

Bedinvetmab 1

Carprofen 1

Desoxycortone Pivalate 1

Prednisone 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Joint ache (#2427 of 2,481 by report volume); death-coded 9.1%. PlainBreed reaction plate · report volume stamp 11 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →