Reaction profile

The FDA adverse-event record for chewing at injection site

23 FDA reports name chewing at injection site, a lower-volume reaction in the CVM extract (VeDDRA 3053). Plate stamps and neighbourhood peers follow.

#2105 of 2,481
by report volume (all reactions)
23
reports citing this reaction
0.0%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Chewing at injection site has 23 reports now versus 20 in that prior snapshot: 3 more (15.0%).

Report change
+3
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Chewing at injection site changes

FDA AER · VeDDRA plate

Code 3053 VOL-TRACE

VOL-TRACE · DEATH-RARE · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 23 reports
  • DEATH-RARE 0.0%
  • LOWER-Q #2105/2481
  • PHOTO-FINISH Anal oedema
  • SPECIES-DOG Dog · 23
  • DRUG-LEAD Tigilanol Tiglate · 10
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anal oedema (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Chewing at injection site

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Anal oedema · near23Boil · near23Cervical spondylopathy · near23Chewing at injection… · this…23CORTISOL:CREATININE H… · near23Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Chewing at injection site

Chewing at injection site: low death-coded share in the FDA AER plate

Signature read: Chewing at injection site's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is lower-third scale: 23 named reports in the openFDA extract. Death-coded share is lower-third: 0 of 23 reports (0.0% of named reports). Nearest volume peer: Anal oedema (±0 reports). Lead species Dog (23). Lead co-reported drug Tigilanol Tiglate (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Tigilanol Tiglate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 23

Breeds Most Affected

Retriever - Labrador 6
Retriever - Golden 3
Shih Tzu 3
Dog (unknown) 2
Siberian Husky 2
Pug 2
Chihuahua 2
Sheepdog - Shetland 1
Shepherd (unspecified) 1
Pointing Dog - Hungarian Short-haired (Vizsla) 1

Associated Drugs

Tigilanol Tiglate 10
Gabapentin 8
Diphenhydramine 8
Bedinvetmab 6
Butorphanol 5
Maropitant Citrate 5
Famotidine 4
Dexmedetomidine 3
Atipamezole 3
Afoxolaner 3
Oclacitinib Maleate 3
Dexamethasone Sp 3
Lrs Fluids 3
Prednisone 3
Milbemycin, Praziquantel 2
Maropitant 2
Milbemycin Oxime + Praziquantel 2
Medetomidine 2
Methadone 2
Fluralaner Powder For Inj Susp 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Chewing at injection site (#2105 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →