Chewing at injection site

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VeDDRA Code: 3053

19 adverse event reports referencing this reaction

19
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Dog 19

Breeds Most Affected

Retriever - Labrador 6
Retriever - Golden 3
Siberian Husky 2
Pug 2
Dog (unknown) 1
Shepherd (unspecified) 1
Sheepdog - Shetland 1
Pointing Dog - Hungarian Short-haired (Vizsla) 1
Chihuahua 1
Shih Tzu 1

Associated Drugs

Tigilanol Tiglate 9
Gabapentin 8
Diphenhydramine 7
Bedinvetmab 6
Butorphanol 5
Maropitant Citrate 5
Famotidine 4
Dexmedetomidine 3
Atipamezole 3
Dexamethasone Sp 3
Lrs Fluids 3
Afoxolaner 3
Prednisone 3
Oclacitinib Maleate 2
Maropitant 2
Medetomidine 2
Milbemycin, Praziquantel 2
Methadone 2
Acepromazine 1
Prednisolone 1

Data Summary

Metric Value
Total reports referencing reaction 19
Reports with fatal outcome 0
Case-fatality rate (reported events) 0.0%
Species observed 1
Breeds observed 10
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 3053.

Chewing at injection site Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 19 adverse event reports that reference Chewing at injection site as a reaction term, including 0 reports with a death outcome — a 0.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 3053, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Chewing at injection site appears most frequently in reports for Dog (19 reports) — with Dog dominating at 19 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (6), Retriever - Golden (3), Siberian Husky (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Chewing at injection site are Tigilanol Tiglate (9 reports), Gabapentin (8 reports), Diphenhydramine (7 reports), Bedinvetmab (6 reports), with Tigilanol Tiglate appearing alongside this reaction in 9 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial