Reaction profile

The FDA adverse-event record for cognitive disorder nos

283 FDA adverse-event reports reference cognitive disorder nos (VeDDRA 1382). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#894 of 2,481
by report volume (all reactions)
283
reports citing this reaction
27.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cognitive disorder NOS has 283 reports now versus 275 in that prior snapshot: 8 more (2.9%).

Report change
+8
Death-coded reports
+4
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cognitive disorder NOS changes

FDA AER · VeDDRA plate

Code 1382 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 283 reports
  • DEATH-HOT 27.6%
  • MID-PACK #894/2481
  • PHOTO-FINISH Cardiomyopathy
  • SPECIES-DOG Dog · 269
  • DRUG-LEAD Bedinvetmab · 135
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cardiomyopathy (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Cognitive disorder NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cardiomyopathy · near283Cognitive disorder NOS · thi…283Injection site serosa… · near283Lack of efficacy (fun… · near283Peeling skin · near283Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Cognitive disorder NOS

Cognitive disorder NOS: high death-coded share in the FDA AER plate

Signature read: 78 death-coded reports is a heavy tail count for Cognitive disorder NOS in the CVM extract. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 78 of 283 reports (27.6% of named reports). Nearest volume peer: Cardiomyopathy (±0 reports). Lead species Dog (269). Lead co-reported drug Bedinvetmab (135).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 269
Cat 13
Human 1

Breeds Most Affected

Retriever - Labrador 26
Dog (unknown) 22
Crossbred Canine/dog 16
Chihuahua 14
Beagle 11
Terrier - Bull - American Pit 10
Terrier - Yorkshire 9
Shepherd Dog - Australian 9
Terrier - Jack Russell 8
Shepherd Dog - German 8

Associated Drugs

Bedinvetmab 135
Trilostane 77
Carprofen 34
Gabapentin 30
Milbemycin Oxime + Spinosad 10
Grapiprant 10
Pimobendan 10
Pyrantel Pamoate;Sarolaner 9
Trazodone 9
Galliprant 9
Enalapril 8
Fluralaner 13.64% 12-Week Chew 8
Denamarin 6
Afoxolaner 5
Alprazolam 5
Prednisone 5
Tramadol 5
Metronidazole 5
Frunevetmab 5
Keppra 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Cognitive disorder NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (27.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cognitive disorder NOS (#894 of 2,481 by report volume); death-coded 27.6%. PlainBreed reaction plate · death-coded report count stamp 78 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →