Reaction profile

The FDA adverse-event record for lack of efficacy (ectoparasite) - mite nos

287 FDA adverse-event reports reference lack of efficacy (ectoparasite) - mite nos (VeDDRA 2652). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#888 of 2,481
by report volume (all reactions)
287
reports citing this reaction
1.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of efficacy (ectoparasite) - mite NOS has 287 reports now versus 284 in that prior snapshot: 3 more (1.1%).

Report change
+3
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of efficacy (ectoparasite) - mite NOS changes

FDA AER · VeDDRA plate

Code 2652 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 287 reports
  • DEATH-LOW 1.7%
  • MID-PACK #888/2481
  • PHOTO-FINISH Foam in the mouth
  • SPECIES-DOG Dog · 134
  • DRUG-LEAD Selamectin · 62
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Foam in the mouth (±1 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lack of efficacy - mite NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site derm… · near289Foam in the mouth · near288Tongue ulceration · near288Lack of efficacy (ect… · thi…287Impaired propriocepti… · near286Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of efficacy (ectoparasite) - mite NOS

Lack of efficacy (ectoparasite) - mite NOS: low death-coded share in the FDA AER plate

Signature read: Lack of efficacy (ectoparasite) - mite NOS's 1.7% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 5 of 287 reports (1.7% of named reports). Nearest volume peer: Foam in the mouth (±1 reports). Lead species Dog (134). Lead co-reported drug Selamectin (62).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Selamectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 134
Cattle 71
Cat 68
Pig 7
Rabbit 4
Guinea Pig 1
Sheep 1
Ferret 1

Breeds Most Affected

Dog (unknown) 41
Holstein-Friesian also known as Holstein 27
Domestic Shorthair 21
Cat (other) 18
Cattle (unknown) 17
Cat (unknown) 14
Retriever - Labrador 10
Crossbred Canine/dog 10
Shepherd Dog - German 8
Cattle (other) 8

Associated Drugs

Selamectin 62
Fluralaner 13.64% 12-Week Chew 30
Afoxolaner 23
Eprinomectin 21
Ivermectin 19
Fluralaner Spot-On Solution 15
Pyrantel Pamoate;Sarolaner 14
Eprinomectin 5 Mg/Ml Pour-On Solution 12
Selamectin;Sarolaner 12
Moxidectin 10
Doramectin 7
Lotilaner 7
Imidacloprid + Moxidectin 6
Spinosad 4
Eprinomectin 0.5% Pour-On 4
Ivermectin 0.5% Pour-On Topical Solution 4
Milbemycin Oxime 4
Fluralaner 5.46% 1-Month Chew 4
Eprinomectin Topical 3
Ivermectin 0.5% Pour-On 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lack of efficacy (ectoparasite) - mite NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (287 here).

Similar death-coded share

Nearest other reactions by death-coded share (1.7% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of efficacy (ectoparasite) - mite NOS (#888 of 2,481 by report volume); death-coded 1.7%. PlainBreed reaction plate · death-coded share stamp 1.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →