Reaction profile

The FDA adverse-event record for necrotizing pancreatitis

38 FDA reports name necrotizing pancreatitis, a lower-volume reaction in the CVM extract (VeDDRA 1893). Plate stamps and neighbourhood peers follow.

#1883 of 2,481
by report volume (all reactions)
38
reports citing this reaction
81.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Necrotizing pancreatitis has 38 reports now versus 37 in that prior snapshot: 1 more (2.7%).

Report change
+1
Death-coded reports
+0
Death-coded share
−2.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Necrotizing pancreatitis changes

FDA AER · VeDDRA plate

Code 1893 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 38 reports
  • DEATH-HOT 81.6%
  • LOWER-Q #1883/2481
  • PHOTO-FINISH Clenched jaw
  • SPECIES-DOG Dog · 27
  • DRUG-LEAD Maropitant Citrate · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Clenched jaw (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Necrotizing pancreatitis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Clenched jaw · near38Conjunctival reddening · near38Disturbance in attent… · near38Duodenitis · near38Necrotizing pancreati… · thi…38Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Necrotizing pancreatitis

Necrotizing pancreatitis: high death-coded share in the FDA AER plate

Signature read: Necrotizing pancreatitis's 81.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 38 named reports in the openFDA extract. Death-coded share is upper-third: 31 of 38 reports (81.6% of named reports). Nearest volume peer: Clenched jaw (±0 reports). Lead species Dog (27). Lead co-reported drug Maropitant Citrate (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 27
Cat 11

Breeds Most Affected

Domestic Shorthair 8
Crossbred Canine/dog 4
Terrier - Yorkshire 3
Retriever - Labrador 2
Beagle 2
Shih Tzu 2
Chihuahua 2
Deutsche Dogge, Great Dane 2
Corgi - Welsh Cardigan 1
Maine Coon 1

Associated Drugs

Maropitant Citrate 8
Carprofen 7
Milbemycin Oxime + Spinosad 6
Meloxicam 5
Propofol 4
Robenacoxib 4
Cefazolin 3
Buprenorphine 3
Bexagliflozin 3
Isoflurane 3
Spinosad 2
Ivermectin 2
Fluids 2
Enrofloxacin 2
Fluralaner Chew Tablets 2
Fuzapladib Sodium 2
Pradofloxacin 2
Fluid Therapy (Unknown) 2
Ivermectin + Pyrantel 1
Doxycycline 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Necrotizing pancreatitis (#1883 of 2,481 by report volume); death-coded 81.6%. PlainBreed reaction plate · death-coded share stamp 81.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →