Reaction profile

The FDA adverse-event record for necrotizing pancreatitis

36 FDA adverse-event reports reference necrotizing pancreatitis (VeDDRA 1893). See the species, breeds, and drugs most associated with it below.

36
reports citing this reaction
83.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
36
Total Reports
30
Deaths
83.3%
Death Rate

Species Most Affected

Dog 25
Cat 11

Breeds Most Affected

Domestic Shorthair 8
Terrier - Yorkshire 3
Crossbred Canine/dog 3
Retriever - Labrador 2
Beagle 2
Chihuahua 2
Deutsche Dogge, Great Dane 2
Corgi - Welsh Cardigan 1
Maine Coon 1
Shih Tzu 1

Associated Drugs

Carprofen 7
Maropitant Citrate 7
Milbemycin Oxime + Spinosad 6
Meloxicam 5
Propofol 4
Robenacoxib 4
Cefazolin 3
Buprenorphine 3
Bexagliflozin 3
Spinosad 2
Ivermectin 2
Fluids 2
Fluralaner Chew Tablets 2
Fuzapladib Sodium 2
Isoflurane 2
Pradofloxacin 2
Fluid Therapy (Unknown) 2
Ivermectin + Pyrantel 1
Doxycycline 1
Sucralfate 1

Necrotizing pancreatitis Reaction Insights

36 reports name Necrotizing pancreatitis; 30 recorded a death outcome (83.3% of reported events, not a population-level mortality rate). VeDDRA code: 1893.

By species: Dog (25 reports), Cat (11 reports). By breed: Domestic Shorthair (8), Terrier - Yorkshire (3), Crossbred Canine/dog (3).

Most co-reported drugs: Carprofen (7 reports), Maropitant Citrate (7 reports), Milbemycin Oxime + Spinosad (6 reports), Meloxicam (5 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.