Reaction profile

The FDA adverse-event record for urinary bladder disorder nos

601 FDA adverse-event reports reference urinary bladder disorder nos (VeDDRA 732). See the species, breeds, and drugs most associated with it below.

601
reports citing this reaction
26.3%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
601
Total Reports
158
Deaths
26.3%
Death Rate

Species Most Affected

Dog 444
Cat 152
Horse 2
Unknown 1
Human 1
Hedgehog 1

Breeds Most Affected

Domestic Shorthair 108
Retriever - Labrador 51
Crossbred Canine/dog 25
Retriever - Golden 20
Dog (unknown) 16
Shepherd Dog - German 14
Shih Tzu 14
Terrier - Yorkshire 14
Maltese 14
Domestic Longhair 12

Associated Drugs

Milbemycin Oxime + Spinosad 68
Oclacitinib Maleate 62
Carprofen 58
Maropitant Citrate 47
Buprenorphine 42
Bedinvetmab 42
Cefovecin 39
Gabapentin 39
Trilostane 33
Spinosad 31
Selamectin 23
Famotidine 21
Enrofloxacin 20
Prednisone 20
Robenacoxib 19
Butorphanol 16
Fluralaner Chew Tablets 16
Afoxolaner 15
Metronidazole 13
Ketamine 13

Urinary bladder disorder NOS Reaction Insights

601 reports name Urinary bladder disorder NOS; 158 recorded a death outcome (26.3% of reported events, not a population-level mortality rate). VeDDRA code: 732.

By species: Dog (444 reports), Cat (152 reports), Horse (2 reports). By breed: Domestic Shorthair (108), Retriever - Labrador (51), Crossbred Canine/dog (25).

Most co-reported drugs: Milbemycin Oxime + Spinosad (68 reports), Oclacitinib Maleate (62 reports), Carprofen (58 reports), Maropitant Citrate (47 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.