Urinary bladder disorder NOS

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VeDDRA Code: 732

601 adverse event reports referencing this reaction

601
Total Reports
158
Deaths
2630.0%
Death Rate

Species Most Affected

Dog 444
Cat 152
Horse 2
Unknown 1
Human 1
Hedgehog 1

Breeds Most Affected

Domestic Shorthair 108
Retriever - Labrador 51
Crossbred Canine/dog 25
Retriever - Golden 20
Dog (unknown) 16
Shepherd Dog - German 14
Shih Tzu 14
Terrier - Yorkshire 14
Maltese 14
Domestic Longhair 12

Associated Drugs

Milbemycin Oxime + Spinosad 68
Oclacitinib Maleate 62
Carprofen 58
Maropitant Citrate 47
Buprenorphine 42
Bedinvetmab 42
Cefovecin 39
Gabapentin 39
Trilostane 33
Spinosad 31
Selamectin 23
Famotidine 21
Enrofloxacin 20
Prednisone 20
Robenacoxib 19
Butorphanol 16
Fluralaner Chew Tablets 16
Afoxolaner 15
Metronidazole 13
Ketamine 13

Data Summary

Metric Value
Total reports referencing reaction 601
Reports with fatal outcome 158
Case-fatality rate (reported events) 2630.0%
Species observed 6
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 732.

Urinary bladder disorder NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 601 adverse event reports that reference Urinary bladder disorder NOS as a reaction term, including 158 reports with a death outcome — a 2630.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 732, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Urinary bladder disorder NOS appears most frequently in reports for Dog (444 reports), Cat (152 reports), Horse (2 reports) — with Dog dominating at 444 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (108), Retriever - Labrador (51), Crossbred Canine/dog (25). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Urinary bladder disorder NOS are Milbemycin Oxime + Spinosad (68 reports), Oclacitinib Maleate (62 reports), Carprofen (58 reports), Maropitant Citrate (47 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 68 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial