Reaction profile

The FDA adverse-event record for hearing decreased

379 FDA adverse-event reports reference hearing decreased (VeDDRA 1512). See the species, breeds, and drugs most associated with it below.

379
reports citing this reaction
4.2%
death-coded share
Dog
most-affected species
Betamethasone + Florfenicol + Terbinafine
most-associated drug
Verify with FDA CVM →
379
Total Reports
16
Deaths
4.2%
Death Rate

Species Most Affected

Dog 366
Cat 12
Human 1

Breeds Most Affected

Retriever - Labrador 32
Crossbred Canine/dog 23
Terrier - Yorkshire 21
Chihuahua 16
Shih Tzu 14
Pug 14
Shepherd Dog - German 12
Boxer (German Boxer) 12
Maltese 12
Retriever - Golden 11

Associated Drugs

Betamethasone + Florfenicol + Terbinafine 75
Miconazole + Polymyxin B + Prednisolone 67
Genta/Momet/Clotrim Ear Oint 38
Bedinvetmab 29
Oclacitinib Maleate 26
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 26
Miconazole Nitrate + Polymyxin B Sulfate + Prednisolone Acetate 15
Milbemycin Oxime + Spinosad 15
Orbiflox/Momet/Posaco Eardrops 13
Trilostane 12
Ear Cleaner (Unknown) 12
Carprofen 11
Ivermectin 10
Florfenicol/Terbinafine Hydrochloride/Mometasone Furoate 10
Prednisone 9
Maropitant Citrate 9
Gabapentin 9
Florfenicol, Terbinafine, Betamethasone Acetate 8
Meloxicam 7
Betamethasone Valerate, Usp + Clotrimazole, Usp + Gentamicin Sulfate, Usp 7

Hearing decreased Reaction Insights

379 reports name Hearing decreased; 16 recorded a death outcome (4.2% of reported events, not a population-level mortality rate). VeDDRA code: 1512.

By species: Dog (366 reports), Cat (12 reports), Human (1 reports). By breed: Retriever - Labrador (32), Crossbred Canine/dog (23), Terrier - Yorkshire (21).

Most co-reported drugs: Betamethasone + Florfenicol + Terbinafine (75 reports), Miconazole + Polymyxin B + Prednisolone (67 reports), Genta/Momet/Clotrim Ear Oint (38 reports), Bedinvetmab (29 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.