Reaction profile

The FDA adverse-event record for elevated serum lipids

25 FDA reports name elevated serum lipids, a lower-volume reaction in the CVM extract (VeDDRA 2667). Plate stamps and neighbourhood peers follow.

#2069 of 2,481
by report volume (all reactions)
25
reports citing this reaction
4.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Elevated serum lipids has 25 reports now versus 24 in that prior snapshot: 1 more (4.2%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Elevated serum lipids changes

FDA AER · VeDDRA plate

Code 2667 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 25 reports
  • DEATH-LOW 4.0%
  • LOWER-Q #2069/2481
  • PHOTO-FINISH Abnormal behaviour NOS
  • SPECIES-DOG Dog · 14
  • DRUG-LEAD Trilostane · 8
  • DESK-WIDE 18 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal behaviour NOS (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Elevated serum lipids

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abnormal behaviour NOS · near25Buccal ulceration · near25Dizzy spell · near25Elevated serum lipids · this…25HCO3 LOW, BLOOD · near25Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Elevated serum lipids

Elevated serum lipids: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Elevated serum lipids in the CVM extract. Report volume is lower-third scale: 25 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 25 reports (4.0% of named reports). Nearest volume peer: Abnormal behaviour NOS (±0 reports). Lead species Dog (14). Lead co-reported drug Trilostane (8).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Trilostane appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14
Cat 10
Horse 1

Breeds Most Affected

Domestic Shorthair 6
Domestic Longhair 2
Shepherd Dog - Australian 2
Terrier - Jack Russell 1
Terrier (unspecified) 1
Poodle - Miniature 1
Bichon Frise 1
Retriever - Golden 1
Deutsche Dogge, Great Dane 1
Dog (unknown) 1

Associated Drugs

Trilostane 8
Bexagliflozin 6
Ivermectin + Pyrantel As Pamoate Salt 3
Afoxolaner 2
Fipronil + Pyriproxyfen + S-Methoprene 2
Bedinvetmab 2
Oclacitinib Maleate 2
Insulin Regular 1
Orbiflox/Momet/Posaco Eardrops 1
Fluralaner 13.64% 12-Week Chew 1
Cefovecin Sodium 1
Prescription Diet 1
Triglycerides 1
Anti-Il31 Mab Mcs Lot #1283563 1
Hydroxyzine 1
Unspecified Thyroid Medication 1
Hydrolyzed Protein Diet 1
Triamcinolone Injection 1
Sirolimus 1
Hypoallergenic Diet (Unknown) 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated serum lipids (#2069 of 2,481 by report volume); death-coded 4.0%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →