Reaction profile

The FDA adverse-event record for application site mucopurulent discharge

132 FDA adverse-event reports reference application site mucopurulent discharge (VeDDRA 17). See the species, breeds, and drugs most associated with it below.

132
reports citing this reaction
2.3%
death-coded share
Cat
most-affected species
Imidacloprid + Moxidectin
most-associated drug
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132
Total Reports
3
Deaths
2.3%
Death Rate

Species Most Affected

Cat 73
Dog 56
Cattle 2
Horse 1

Breeds Most Affected

Domestic Shorthair 51
Retriever - Labrador 7
Retriever - Golden 7
Dog (unknown) 7
Crossbred Canine/dog 6
Domestic Mediumhair 6
Domestic Longhair 4
Shih Tzu 3
Maltese 3
Persian 3

Associated Drugs

Imidacloprid + Moxidectin 23
Selamectin 22
Flumethrin-Imidacloprid 13
Emodepside + Praziquantel 11
Fluralaner Spot-On Solution 10
Selamectin;Sarolaner 8
Enrofloxacin 6
Rabies Vaccine 6
Dexamethasone 6
Fluralaner/Moxidectin Spot-On 6
Prednisone 5
Cefovecin Sodium 5
Diphenhydramine 4
Feline Viral Rhinotracheitis, Calicivirus And Panleukopenia Vaccine 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Florfenicol, Terbinafine, Betamethasone Acetate 4
Tacrolimus 4
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Amoxicillin/Clavulanic Acid 3

Application site mucopurulent discharge Reaction Insights

132 reports name Application site mucopurulent discharge; 3 recorded a death outcome (2.3% of reported events, not a population-level mortality rate). VeDDRA code: 17.

By species: Cat (73 reports), Dog (56 reports), Cattle (2 reports). By breed: Domestic Shorthair (51), Retriever - Labrador (7), Retriever - Golden (7).

Most co-reported drugs: Imidacloprid + Moxidectin (23 reports), Selamectin (22 reports), Flumethrin-Imidacloprid (13 reports), Emodepside + Praziquantel (11 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.