Application site mucopurulent discharge

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VeDDRA Code: 17

132 adverse event reports referencing this reaction

132
Total Reports
3
Deaths
230.0%
Death Rate

Species Most Affected

Cat 73
Dog 56
Cattle 2
Horse 1

Breeds Most Affected

Domestic Shorthair 51
Retriever - Labrador 7
Retriever - Golden 7
Dog (unknown) 7
Crossbred Canine/dog 6
Domestic Mediumhair 6
Domestic Longhair 4
Shih Tzu 3
Maltese 3
Persian 3

Associated Drugs

Imidacloprid + Moxidectin 23
Selamectin 22
Flumethrin-Imidacloprid 13
Emodepside + Praziquantel 11
Fluralaner Spot-On Solution 10
Selamectin;Sarolaner 8
Enrofloxacin 6
Rabies Vaccine 6
Dexamethasone 6
Fluralaner/Moxidectin Spot-On 6
Prednisone 5
Cefovecin Sodium 5
Diphenhydramine 4
Feline Viral Rhinotracheitis, Calicivirus And Panleukopenia Vaccine 4
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 4
Florfenicol, Terbinafine, Betamethasone Acetate 4
Tacrolimus 4
Fipronil 9.8%/S-Methoprene 8.8%/ Amitraz 22.1% Spot-On 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Amoxicillin/Clavulanic Acid 3

Data Summary

Metric Value
Total reports referencing reaction 132
Reports with fatal outcome 3
Case-fatality rate (reported events) 230.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 17.

Application site mucopurulent discharge Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 132 adverse event reports that reference Application site mucopurulent discharge as a reaction term, including 3 reports with a death outcome — a 230.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 17, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Application site mucopurulent discharge appears most frequently in reports for Cat (73 reports), Dog (56 reports), Cattle (2 reports) — with Cat dominating at 73 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (51), Retriever - Labrador (7), Retriever - Golden (7). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Application site mucopurulent discharge are Imidacloprid + Moxidectin (23 reports), Selamectin (22 reports), Flumethrin-Imidacloprid (13 reports), Emodepside + Praziquantel (11 reports), with Imidacloprid + Moxidectin appearing alongside this reaction in 23 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial