Reaction profile

The FDA adverse-event record for erythema (for urticaria see immune soc)

4,509 FDA reports name erythema (for urticaria see immune soc), a high-volume reaction in the CVM extract (VeDDRA 948). Plate stamps and neighbourhood peers follow.

#107 of 2,481
by report volume (all reactions)
4,509
reports citing this reaction
3.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Erythema (for urticaria see Immune SOC) has 4,509 reports now versus 4,480 in that prior snapshot: 29 more (0.6%).

Report change
+29
Death-coded reports
+1
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Erythema (for urticaria see Immune SOC) changes

FDA AER · VeDDRA plate

Code 948 VOL-MID

VOL-MID · DEATH-LOW · TOP-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 4,509 reports
  • DEATH-LOW 3.0%
  • TOP-DECILE #107/2481
  • PHOTO-FINISH Nausea
  • SPECIES-DOG Dog · 3,996
  • DRUG-LEAD Moxidectin · 687
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Nausea (±7 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Erythema

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Falling · near4570Hyperphosphataemia · near4554Erythema (for urticar… · thi…4509Nausea · near4502Intentional misuse · near4443Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Erythema (for urticaria see Immune SOC)

Erythema (for urticaria see Immune SOC): low death-coded share in the FDA AER plate

Signature read: 4,509 reports place Erythema (for urticaria see Immune SOC) in the upper third of FDA AER volume (#107 of 2,481). Report volume is upper-third scale: 4,509 named reports in the openFDA extract. Death-coded share is lower-third: 137 of 4,509 reports (3.0% of named reports). Nearest volume peer: Nausea (±7 reports). Lead species Dog (3,996). Lead co-reported drug Moxidectin (687).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Moxidectin appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 3,996
Cat 396
Human 82
Horse 14
Cattle 7
Pig 6
Rabbit 4
Turkey 1
Donkey 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 382
Domestic Shorthair 255
Chihuahua 229
Crossbred Canine/dog 221
Terrier - Bull - American Pit 213
Terrier - Yorkshire 153
Boxer (German Boxer) 144
Shih Tzu 139
Retriever - Golden 132
Pit Bull 130

Associated Drugs

Moxidectin 687
Afoxolaner 628
Milbemycin Oxime + Spinosad 318
Oclacitinib Maleate 283
Imidacloprid + Moxidectin 251
Maropitant Citrate 199
Carprofen 172
Selamectin 169
Ivermectin + Pyrantel As Pamoate Salt 169
Anti-Il31 Mab Mcs Lot #1283563 151
Prednisone 145
Fluralaner Chew Tablets 143
Cefovecin 142
Diphenhydramine Hcl 115
Spinosad 112
Phenylpropanolamine Hcl 106
Diphenhydramine 90
Dexamethasone 82
Melarsomine Dihydrochloride 72
Enrofloxacin 72

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Erythema (for urticaria see Immune SOC), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (4,509 here).

Similar death-coded share

Nearest other reactions by death-coded share (3.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Erythema (for urticaria see Immune SOC) (#107 of 2,481 by report volume); death-coded 3.0%. PlainBreed reaction plate · report volume stamp 4,509 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →