Erythema (for urticaria see Immune SOC)
VeDDRA Code: 948
4,428 adverse event reports referencing this reaction
Species Most Affected
Breeds Most Affected
Associated Drugs
Data Summary
| Metric | Value |
|---|---|
| Total reports referencing reaction | 4,428 |
| Reports with fatal outcome | 133 |
| Case-fatality rate (reported events) | 300.0% |
| Species observed | 10 |
| Breeds observed | 20 |
| Drugs associated with reaction | 20 |
Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 948.
Erythema (for urticaria see Immune SOC) Reaction Insights
The FDA Center for Veterinary Medicine database currently lists 4,428 adverse event reports that reference Erythema (for urticaria see Immune SOC) as a reaction term, including 133 reports with a death outcome — a 300.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 948, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.
Erythema (for urticaria see Immune SOC) appears most frequently in reports for Dog (3,926 reports), Cat (385 reports), Human (82 reports) — with Dog dominating at 3,926 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (378), Domestic Shorthair (250), Chihuahua (227). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.
The drugs most commonly co-reported with Erythema (for urticaria see Immune SOC) are Moxidectin (673 reports), Afoxolaner (626 reports), Milbemycin Oxime + Spinosad (317 reports), Oclacitinib Maleate (270 reports), with Moxidectin appearing alongside this reaction in 673 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.
Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates
Read our methodology — how this data is sourced, computed, and verified.