Reaction profile

The FDA adverse-event record for splenic neoplasm nos

157 FDA adverse-event reports reference splenic neoplasm nos (VeDDRA 1977). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1160 of 2,481
by report volume (all reactions)
157
reports citing this reaction
51.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Splenic neoplasm NOS has 157 reports now versus 149 in that prior snapshot: 8 more (5.4%).

Report change
+8
Death-coded reports
+5
Death-coded share
+0.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Splenic neoplasm NOS changes

FDA AER · VeDDRA plate

Code 1977 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 157 reports
  • DEATH-HOT 51.0%
  • MID-PACK #1160/2481
  • PHOTO-FINISH Accidental drug intak…
  • SPECIES-DOG Dog · 152
  • DRUG-LEAD Bedinvetmab · 104
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Accidental drug intake by child (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Splenic neoplasm NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site dry… · near158Accidental drug intak… · near157Splenic neoplasm NOS · this …157Throat irritation · near157Abnormal necropsy fin… · near156Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Splenic neoplasm NOS

Splenic neoplasm NOS: high death-coded share in the FDA AER plate

Signature read: Splenic neoplasm NOS's 51.0% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 80 of 157 reports (51.0% of named reports). Nearest volume peer: Accidental drug intake by child (±0 reports). Lead species Dog (152). Lead co-reported drug Bedinvetmab (104).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 152
Cat 5

Breeds Most Affected

Retriever - Labrador 24
Retriever - Golden 13
Terrier - Bull - American Pit 13
Shepherd Dog - German 10
Dog (unknown) 9
Collie - Border 9
Crossbred Canine/dog 8
Boxer (German Boxer) 6
Shepherd Dog - Australian 5
Shepherd (unspecified) 4

Associated Drugs

Bedinvetmab 104
Gabapentin 29
Carprofen 26
Oclacitinib Maleate 17
Grapiprant 10
Anti-Il31 Mab Mcs Lot #1283563 10
Galliprant 10
Maropitant Citrate 9
Prednisone 7
Afoxolaner 6
Joint Supplement 5
Adequan 4
Moxidectin 4
Rabies Vaccine 4
Trilostane 4
Fluralaner 13.64% 12-Week Chew 4
Fish Oil 4
Deracoxib 3
Methocarbamol 3
Pyrantel Pamoate;Sarolaner 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Splenic neoplasm NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (51.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Splenic neoplasm NOS (#1160 of 2,481 by report volume); death-coded 51.0%. PlainBreed reaction plate · death-coded share stamp 51.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →