Reaction profile

The FDA adverse-event record for quadriparesis

141 FDA adverse-event reports reference quadriparesis (VeDDRA 700). See the species, breeds, and drugs most associated with it below.

141
reports citing this reaction
27.0%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
141
Total Reports
38
Deaths
27.0%
Death Rate

Species Most Affected

Dog 119
Cat 21
Horse 1

Breeds Most Affected

Domestic Shorthair 17
Retriever - Labrador 17
Shepherd Dog - German 12
Retriever - Golden 7
Shih Tzu 6
Crossbred Canine/dog 5
Terrier - Yorkshire 5
Siberian Husky 4
Rottweiler 4
Dog (unknown) 4

Associated Drugs

Carprofen 19
Bedinvetmab 19
Maropitant Citrate 13
Milbemycin Oxime + Spinosad 12
Moxidectin 10
Afoxolaner 10
Gabapentin 10
Pyrantel Pamoate;Sarolaner 8
Tramadol 7
Prednisone 7
Fluralaner 13.64% 12-Week Chew 7
Buprenorphine 6
Sarolaner 6
Fluralaner Chew Tablets 6
Propofol 5
Selamectin 5
Meloxicam 5
Oclacitinib Maleate 5
Diazepam 5
Trilostane 4

Quadriparesis Reaction Insights

141 reports name Quadriparesis; 38 recorded a death outcome (27.0% of reported events, not a population-level mortality rate). VeDDRA code: 700.

By species: Dog (119 reports), Cat (21 reports), Horse (1 reports). By breed: Domestic Shorthair (17), Retriever - Labrador (17), Shepherd Dog - German (12).

Most co-reported drugs: Carprofen (19 reports), Bedinvetmab (19 reports), Maropitant Citrate (13 reports), Milbemycin Oxime + Spinosad (12 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.