Reaction profile

The FDA adverse-event record for quadriparesis

150 FDA adverse-event reports reference quadriparesis (VeDDRA 700). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1187 of 2,481
by report volume (all reactions)
150
reports citing this reaction
29.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Quadriparesis has 150 reports now versus 148 in that prior snapshot: 2 more (1.4%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Quadriparesis changes

FDA AER · VeDDRA plate

Code 700 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 150 reports
  • DEATH-HOT 29.3%
  • MID-PACK #1187/2481
  • PHOTO-FINISH Abnormal histology NOS
  • SPECIES-DOG Dog · 123
  • DRUG-LEAD Bedinvetmab · 23
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abnormal histology NOS (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Quadriparesis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Abnormal histology NOS · near150Application site exco… · near150Ligament rupture · near150Nephropathy · near150Quadriparesis · this reaction150Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Quadriparesis

Quadriparesis: high death-coded share in the FDA AER plate

Signature read: Quadriparesis's 29.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 44 of 150 reports (29.3% of named reports). Nearest volume peer: Abnormal histology NOS (±0 reports). Lead species Dog (123). Lead co-reported drug Bedinvetmab (23).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 123
Cat 26
Horse 1

Breeds Most Affected

Domestic Shorthair 22
Retriever - Labrador 19
Shepherd Dog - German 12
Retriever - Golden 7
Shih Tzu 6
Crossbred Canine/dog 6
Terrier - Yorkshire 5
Siberian Husky 4
Rottweiler 4
Dog (unknown) 4

Associated Drugs

Bedinvetmab 23
Carprofen 20
Maropitant Citrate 14
Milbemycin Oxime + Spinosad 12
Gabapentin 11
Moxidectin 10
Afoxolaner 10
Pyrantel Pamoate;Sarolaner 8
Tramadol 7
Prednisone 7
Fluralaner 13.64% 12-Week Chew 7
Buprenorphine 6
Selamectin 6
Fluralaner Chew Tablets 6
Sarolaner 6
Ivermectin 5
Propofol 5
Meloxicam 5
Oclacitinib Maleate 5
Diazepam 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Quadriparesis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (150 here).

Similar death-coded share

Nearest other reactions by death-coded share (29.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Quadriparesis (#1187 of 2,481 by report volume); death-coded 29.3%. PlainBreed reaction plate · death-coded share stamp 29.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →