Reaction profile

The FDA adverse-event record for lack of efficacy (neoplasia, partial remission)

86 FDA adverse-event reports reference lack of efficacy (neoplasia, partial remission) (VeDDRA 2892). See the species, breeds, and drugs most associated with it below.

86
reports citing this reaction
2.3%
death-coded share
Dog
most-affected species
Prednisone
most-associated drug
Verify with FDA CVM →
86
Total Reports
2
Deaths
2.3%
Death Rate

Species Most Affected

Dog 86

Breeds Most Affected

Retriever - Labrador 17
Terrier - Bull - American Pit 7
Dog (unknown) 6
Bulldog - French 6
Chihuahua 5
Pit Bull 5
Mountain Dog - Bernese 4
Boxer (German Boxer) 4
Terrier (unspecified) 4
Shepherd Dog - German 3

Associated Drugs

Prednisone 73
Diphenhydramine 69
Famotidine 68
Tigilanol Tiglate 59
Gabapentin 50
Butorphanol Tartrate 40
Dexmedetomidine Hydrochloride 32
Atipamezole Hydrochloride 28
Maropitant Citrate 23
Butorphanol 17
Trazodone 12
Propofol 11
Buprenorphine 10
Dexmedetomidine 10
Oclacitinib Maleate 7
Midazolam 7
Isoflurane 6
Dexamethasone 6
Alfaxalone 6
Prednisolone 6

Lack of efficacy (neoplasia, partial remission) Reaction Insights

86 reports name Lack of efficacy (neoplasia, partial remission); 2 recorded a death outcome (2.3% of reported events, not a population-level mortality rate). VeDDRA code: 2892.

By species: Dog (86 reports). By breed: Retriever - Labrador (17), Terrier - Bull - American Pit (7), Dog (unknown) (6).

Most co-reported drugs: Prednisone (73 reports), Diphenhydramine (69 reports), Famotidine (68 reports), Tigilanol Tiglate (59 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.