Reaction profile

The FDA adverse-event record for mixed product

240 FDA adverse-event reports reference mixed product (VeDDRA 99956). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#957 of 2,481
by report volume (all reactions)
240
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Mixed Product has 240 reports now versus 237 in that prior snapshot: 3 more (1.3%).

Report change
+3
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Mixed Product changes

FDA AER · VeDDRA plate

Code 99956 VOL-LOW

VOL-LOW · DEATH-RARE · MID-PACK · PHOTO-FINISH · SPECIES-UNKNOWN · DRUG-LEAD · DESK-MID · BOOK-FULL

  • VOL-LOW 240 reports
  • DEATH-RARE 0.0%
  • MID-PACK #957/2481
  • PHOTO-FINISH Grooming disorder
  • SPECIES-UNKNOWN Unknown · 233
  • DRUG-LEAD Afoxolaner · 26
  • DESK-MID 6 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Grooming disorder (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Mixed Product

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Bronchitis · near241Grooming disorder · near240Mixed Product · this reaction240Aural haematoma · near239Oral mass · near239Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Mixed Product

Mixed Product: low death-coded share in the FDA AER plate

Signature read: Mixed Product's 0.0% death-coded share is among the lowest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is lower-third: 0 of 240 reports (0.0% of named reports). Nearest volume peer: Grooming disorder (±0 reports). Lead species Unknown (233). Lead co-reported drug Afoxolaner (26).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Afoxolaner appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Unknown 233
Dog 4
Cat 2
Human 1

Breeds Most Affected

Unknown 234
Domestic Shorthair 2
Terrier - Yorkshire 1
Papillon - Spaniel - Continental Toy (with erect ears or with dropped ears (Phaléne)) 1
Schnauzer - Miniature 1
Schnauzer (unspecified) 1

Associated Drugs

Afoxolaner 26
Ivermectin + Pyrantel As Pamoate Salt 17
Pimobendan 17
Carprofen 13
Hyaluronic Acid 12
Selamectin 11
Nitenpyram 10
Ivermectin 8
Oclacitinib 8
Milbemycin Oxime + Spinosad 7
Imidacloprid + Moxidectin 6
Meloxicam 5
Praziquantel 5
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 4
Levothyroxine Sodium 4
Sarolaner 4
Afoxolaner 75Mg / Moxidectin 360Mcg / Pyrantel 150Mg Chewable Tablet 4
Penicillin G Procaine 3
Pyrantel Pamoate/Praziquantel 3
Trenbolone Acet/Estradiol Impl 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Mixed Product, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (240 here).

Similar death-coded share

Nearest other reactions by death-coded share (0.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Mixed Product (#957 of 2,481 by report volume); death-coded 0.0%. PlainBreed reaction plate · death-coded share stamp 0.0% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →