Reaction profile
The FDA adverse-event record for swelling nos
1,378 FDA adverse-event reports reference swelling nos (VeDDRA 1214). See the species, breeds, and drugs most associated with it below.
- 1,378
- reports citing this reaction
- 11.2%
- death-coded share
- Dog
- most-affected species
- Tigilanol Tiglate
- most-associated drug
Species Most Affected
Breeds Most Affected
Associated Drugs
Swelling NOS Reaction Insights
1,378 reports name Swelling NOS; 155 recorded a death outcome (11.2% of reported events, not a population-level mortality rate). VeDDRA code: 1214.
By species: Dog (1,118 reports), Cat (107 reports), Horse (68 reports). By breed: Retriever - Labrador (126), Pit Bull (79), Crossbred Canine/dog (72).
Most co-reported drugs: Tigilanol Tiglate (282 reports), Carprofen (111 reports), Milbemycin Oxime + Spinosad (108 reports), Moxidectin (91 reports).
Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.
Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025
Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.