Reaction profile

The FDA adverse-event record for vaginitis

86 FDA adverse-event reports reference vaginitis (VeDDRA 822). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1472 of 2,481
by report volume (all reactions)
86
reports citing this reaction
9.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Vaginitis has 86 reports now versus 85 in that prior snapshot: 1 more (1.2%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Vaginitis changes

FDA AER · VeDDRA plate

Code 822 VOL-LOW

VOL-LOW · DEATH-PAR · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 86 reports
  • DEATH-PAR 9.3%
  • MID-PACK #1472/2481
  • PHOTO-FINISH Alkalosis
  • SPECIES-DOG Dog · 73
  • DRUG-LEAD Milbemycin Oxime… · 16
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Alkalosis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Vaginitis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Alkalosis · near86Application site pust… · near86Conjunctival oedema · near86Eyelid inflammation · near86Vaginitis · this reaction86Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Vaginitis

What the FDA AER plate says about Vaginitis

Signature read: 8 death-coded reports is the most distinctive absolute-outcome stamp on Vaginitis. Report volume sits in the middle third of the reaction corpus. 8 of 86 reports were death-coded (9.3% of named reports, not a population mortality rate). Nearest volume peer: Alkalosis (±0 reports). Lead species Dog (73). Lead co-reported drug Milbemycin Oxime + Spinosad (16).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 73
Cattle 11
Goat 2

Breeds Most Affected

Retriever - Golden 8
Aberdeen Angus 6
Crossbred Canine/dog 5
Shepherd Dog - German 5
Retriever - Labrador 4
Dog (unknown) 3
Spaniel (unspecified) 3
Boxer (German Boxer) 3
Bulldog - French 3
Schnauzer (unspecified) 2

Associated Drugs

Milbemycin Oxime + Spinosad 16
Trilostane 14
Progesterone 13
Carprofen 10
Oclacitinib Maleate 7
Milbemycin Oxime + Praziquantel 7
Bedinvetmab 5
Gabapentin 5
Imidacloprid + Moxidectin 4
Afoxolaner 4
Anti-Il31 Mab Mcs Lot #1283563 4
Lotilaner 4
Ivermectin + Pyrantel As Pamoate Salt 3
Prednisone 3
Diphenhydramine 3
Cyclosporine 2
Estriol 2
Maropitant Citrate 2
Cefpodoxime Proxetil 2
Enrofloxacin 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Vaginitis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (86 here).

Similar death-coded share

Nearest other reactions by death-coded share (9.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Vaginitis (#1472 of 2,481 by report volume); death-coded 9.3%. PlainBreed reaction plate · death-coded report count stamp 8 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →