Reaction profile

The FDA adverse-event record for hepatic jaundice

Name: Hepatic jaundice - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://creativecommons.org/publicdomain/zero/1.0/

13 FDA adverse-event reports reference hepatic jaundice (VeDDRA 1278). See the species, breeds, and drugs most associated with it below.

13
reports citing this reaction: 30.8%
death-coded share: Dog
most-affected species: Carprofen
most-associated drug

Compiled by PlainBreed Editorial, Pet Health Editorial Team

Verify with FDA CVM →

Total Reports

Deaths

30.8%

Death Rate

Species Most Affected

Dog 11

Cat 2

Breeds Most Affected

Siberian Husky 2

Retriever - Labrador 2

Ragdoll 1

Terrier - Scottish 1

Dachshund - Miniature 1

Terrier - Bull - Staffordshire 1

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Collie - Smooth-haired 1

Domestic Longhair 1

Great Pyrenees 1

Associated Drugs

Carprofen 6

Omeprazole 2

Maropitant Citrate 2

Famotidine 2

Afoxolaner 2

Maropitant 2

Lactated Ringers 2

Spinosad 1

Canine Adenovirus Type 2, Strain Manhattan, 12-13-76; Canine Distemper Virus, St 1

Meloxicam 1

Fluralaner Chew Tablets 1

Thyroxine 1

Metoclopramide 1

Tramadol 1

Enrofloxacin 1

Desoxycorticosterone Pivalate 1

Prednisolone 1

Dapp Vaccine 1

Lepto Vaccine 1

Rabies Vaccine 1

Hepatic jaundice Reaction Insights

13 reports name Hepatic jaundice; 4 recorded a death outcome (30.8% of reported events, not a population-level mortality rate). VeDDRA code: 1278.

By species: Dog (11 reports), Cat (2 reports). By breed: Siberian Husky (2), Retriever - Labrador (2), Ragdoll (1).

Most co-reported drugs: Carprofen (6 reports), Omeprazole (2 reports), Maropitant Citrate (2 reports), Famotidine (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.