Reaction profile

The FDA adverse-event record for immune-mediated polyarthritis

65 FDA adverse-event reports reference immune-mediated polyarthritis (VeDDRA 2681). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1611 of 2,481
by report volume (all reactions)
65
reports citing this reaction
18.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Immune-mediated polyarthritis has 65 reports now versus 55 in that prior snapshot: 10 more (18.2%).

Report change
+10
Death-coded reports
+2
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Immune-mediated polyarthritis changes

FDA AER · VeDDRA plate

Code 2681 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 65 reports
  • DEATH-ELEV 18.5%
  • MID-PACK #1611/2481
  • PHOTO-FINISH Acne
  • SPECIES-DOG Dog · 61
  • DRUG-LEAD Carprofen · 17
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Acne (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Immune-mediated polyarthritis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Acne · near65Gut sounds decreased · near65Hair standing on end · near65Immune-mediated polya… · thi…65Inversion of albumin/… · near65Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Immune-mediated polyarthritis

What the FDA AER plate says about Immune-mediated polyarthritis

Signature read: report volume at 65 (#1611 of 2,481) is the standout scale stamp on Immune-mediated polyarthritis. Report volume sits in the middle third of the reaction corpus. 12 of 65 reports were death-coded (18.5% of named reports, not a population mortality rate). Nearest volume peer: Acne (±0 reports). Lead species Dog (61). Lead co-reported drug Carprofen (17).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 61
Cat 4

Breeds Most Affected

Retriever - Labrador 14
Crossbred Canine/dog 7
Retriever - Golden 5
Shepherd Dog - Australian 4
Shepherd Dog - German 3
Chihuahua 3
Terrier - Bull - American Pit 2
Domestic Shorthair 2
Dog (unknown) 2
Mountain Dog - Bernese 2

Associated Drugs

Carprofen 17
Bedinvetmab 16
Maropitant Citrate 15
Gabapentin 14
Prednisone 9
Enrofloxacin 9
Pyrantel Pamoate;Sarolaner 8
Doxycycline 7
Oclacitinib Maleate 6
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 6
Anti-Il31 Mab Mcs Lot #1283563 5
Metronidazole 5
Trazodone 5
Dexmedetomidine 5
Rabies Vaccine 5
Famotidine 5
Moxidectin 4
Fluralaner 13.64% 12-Week Chew 4
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 4
Bordetella Bronchiseptica, Strain 78-9159 4

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Immune-mediated polyarthritis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (65 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Immune-mediated polyarthritis (#1611 of 2,481 by report volume); death-coded 18.5%. PlainBreed reaction plate · report volume stamp 65 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →