INEFFECTIVE, GLYCEMIC CONTROL

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VeDDRA Code: 99110

3,063 adverse event reports referencing this reaction

3,063
Total Reports
202
Deaths
660.0%
Death Rate

Species Most Affected

Dog 1,925
Cat 1,130
Unknown 6
Pig 1
Other Porcine 1

Breeds Most Affected

Domestic Shorthair 473
Crossbred Canine/dog 370
Domestic (unspecified) 271
Cat (unknown) 159
Retriever - Labrador 129
Schnauzer - Miniature 123
Terrier - Yorkshire 98
Dog (unknown) 91
Chihuahua 87
Domestic Longhair 79

Associated Drugs

Insulin Injectable Vial 1,858
Protamine Zinc Recombinant Human Insulin 377
Human Insulin 318
Porcine Insulin 236
Recombinant Human Insulin 159
Insulin Injectable Cartridge 88
Trilostane 35
Insulin Pork 31
Insulin 6
Methimazole 4
Fluralaner Chew Tablets 4
Velagliflozin Proline Monohydrate 4
Bexagliflozin 4
Insulin Human 3
Prozinc Human Insulin 3
Prednisone 2
Oclacitinib 2
Syringe Caninsulin/Vetsulin 2
Clavamox 2
Prozinc Care Kits - 100 Ct Syringe Packs 2

Data Summary

Metric Value
Total reports referencing reaction 3,063
Reports with fatal outcome 202
Case-fatality rate (reported events) 660.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 99110.

INEFFECTIVE, GLYCEMIC CONTROL Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 3,063 adverse event reports that reference INEFFECTIVE, GLYCEMIC CONTROL as a reaction term, including 202 reports with a death outcome — a 660.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 99110, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

INEFFECTIVE, GLYCEMIC CONTROL appears most frequently in reports for Dog (1,925 reports), Cat (1,130 reports), Unknown (6 reports) — with Dog dominating at 1,925 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (473), Crossbred Canine/dog (370), Domestic (unspecified) (271). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with INEFFECTIVE, GLYCEMIC CONTROL are Insulin Injectable Vial (1,858 reports), Protamine Zinc Recombinant Human Insulin (377 reports), Human Insulin (318 reports), Porcine Insulin (236 reports), with Insulin Injectable Vial appearing alongside this reaction in 1,858 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial