Reaction profile

The FDA adverse-event record for ineffective, glycemic control

3,063 FDA adverse-event reports reference ineffective, glycemic control (VeDDRA 99110). See the species, breeds, and drugs most associated with it below.

3,063
reports citing this reaction
6.6%
death-coded share
Dog
most-affected species
Insulin Injectable Vial
most-associated drug
Verify with FDA CVM →
3,063
Total Reports
202
Deaths
6.6%
Death Rate

Species Most Affected

Dog 1,925
Cat 1,130
Unknown 6
Pig 1
Other Porcine 1

Breeds Most Affected

Domestic Shorthair 473
Crossbred Canine/dog 370
Domestic (unspecified) 271
Cat (unknown) 159
Retriever - Labrador 129
Schnauzer - Miniature 123
Terrier - Yorkshire 98
Dog (unknown) 91
Chihuahua 87
Domestic Longhair 79

Associated Drugs

Insulin Injectable Vial 1,858
Protamine Zinc Recombinant Human Insulin 377
Human Insulin 318
Porcine Insulin 236
Recombinant Human Insulin 159
Insulin Injectable Cartridge 88
Trilostane 35
Insulin Pork 31
Insulin 6
Methimazole 4
Fluralaner Chew Tablets 4
Velagliflozin Proline Monohydrate 4
Bexagliflozin 4
Insulin Human 3
Prozinc Human Insulin 3
Prednisone 2
Oclacitinib 2
Syringe Caninsulin/Vetsulin 2
Clavamox 2
Prozinc Care Kits - 100 Ct Syringe Packs 2

INEFFECTIVE, GLYCEMIC CONTROL Reaction Insights

3,063 reports name INEFFECTIVE, GLYCEMIC CONTROL; 202 recorded a death outcome (6.6% of reported events, not a population-level mortality rate). VeDDRA code: 99110.

By species: Dog (1,925 reports), Cat (1,130 reports), Unknown (6 reports). By breed: Domestic Shorthair (473), Crossbred Canine/dog (370), Domestic (unspecified) (271).

Most co-reported drugs: Insulin Injectable Vial (1,858 reports), Protamine Zinc Recombinant Human Insulin (377 reports), Human Insulin (318 reports), Porcine Insulin (236 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.