Reaction profile

The FDA adverse-event record for agonal breathing

176 FDA adverse-event reports reference agonal breathing (VeDDRA 2777). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1100 of 2,481
by report volume (all reactions)
176
reports citing this reaction
87.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Agonal breathing has 176 reports now versus 172 in that prior snapshot: 4 more (2.3%).

Report change
+4
Death-coded reports
+4
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Agonal breathing changes

FDA AER · VeDDRA plate

Code 2777 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 176 reports
  • DEATH-HOT 87.5%
  • MID-PACK #1100/2481
  • PHOTO-FINISH Ear canal disorder
  • SPECIES-DOG Dog · 112
  • DRUG-LEAD Maropitant Citrate · 32
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Ear canal disorder (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Agonal breathing

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Agonal breathing · this reac…176Ear canal disorder · near176Fluid in thorax · near176Gastric distension · near176Lack of awareness · near176Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Agonal breathing

Agonal breathing: high death-coded share in the FDA AER plate

Signature read: Agonal breathing's 87.5% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 154 of 176 reports (87.5% of named reports). Nearest volume peer: Ear canal disorder (±0 reports). Lead species Dog (112). Lead co-reported drug Maropitant Citrate (32).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 112
Cat 58
Horse 3
Pig 1
Goat 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 33
Retriever - Labrador 10
Domestic Longhair 9
Chihuahua 6
Retriever - Golden 5
Dog (unknown) 5
Cat (unknown) 5
Shepherd Dog - German 5
Great Pyrenees 4
Boxer (German Boxer) 4

Associated Drugs

Maropitant Citrate 32
Buprenorphine 19
Bedinvetmab 18
Pentobarbital Sodium + Phenytoin Sodium 16
Fluid Therapy 11
Carprofen 10
Metronidazole 10
Prednisone 9
Cefovecin 8
Frunevetmab 8
Metoclopramide 8
Moxidectin 7
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 7
Rabies Vaccine 7
Enrofloxacin 7
Afoxolaner 6
Trilostane 6
Isoflurane 6
Nitenpyram 6
Dextrose 6

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Agonal breathing, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (176 here).

Similar death-coded share

Nearest other reactions by death-coded share (87.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Agonal breathing (#1100 of 2,481 by report volume); death-coded 87.5%. PlainBreed reaction plate · death-coded share stamp 87.5% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →