Reaction profile

The FDA adverse-event record for dermatosis nos

333 FDA adverse-event reports reference dermatosis nos (VeDDRA 941). See the species, breeds, and drugs most associated with it below.

333
reports citing this reaction
5.4%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
333
Total Reports
18
Deaths
5.4%
Death Rate

Species Most Affected

Dog 309
Cat 16
Human 4
Cattle 3
Wolf 1

Breeds Most Affected

Retriever - Labrador 39
Dog (unknown) 30
Pit Bull 24
Crossbred Canine/dog 18
Shepherd Dog - German 16
Terrier - Yorkshire 10
Shih Tzu 10
Bulldog 10
Chihuahua 9
Terrier (unspecified) 8

Associated Drugs

Milbemycin Oxime + Spinosad 264
Spinosad 27
Ivermectin 19
Afoxolaner 14
Oclacitinib Maleate 11
Cyclosporine 10
Ivermectin + Pyrantel As Pamoate Salt 8
Milbemycin Oxime + Praziquantel 7
Lotilaner 7
Enrofloxacin 6
Rabacfosadine 6
Imidacloprid + Moxidectin 5
Fluralaner Chew Tablets 5
Trilostane 4
Prednisolone 4
Cyclosporine A 4
Lufenuron + Milbemycin Oxime 4
Vaccines (Unknown) 4
Prednisone 4
Rabacfosadine Succinate 4

Dermatosis NOS Reaction Insights

333 reports name Dermatosis NOS; 18 recorded a death outcome (5.4% of reported events, not a population-level mortality rate). VeDDRA code: 941.

By species: Dog (309 reports), Cat (16 reports), Human (4 reports). By breed: Retriever - Labrador (39), Dog (unknown) (30), Pit Bull (24).

Most co-reported drugs: Milbemycin Oxime + Spinosad (264 reports), Spinosad (27 reports), Ivermectin (19 reports), Afoxolaner (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.