Dermatosis NOS

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VeDDRA Code: 941

333 adverse event reports referencing this reaction

333
Total Reports
18
Deaths
540.0%
Death Rate

Species Most Affected

Dog 309
Cat 16
Human 4
Cattle 3
Wolf 1

Breeds Most Affected

Retriever - Labrador 39
Dog (unknown) 30
Pit Bull 24
Crossbred Canine/dog 18
Shepherd Dog - German 16
Terrier - Yorkshire 10
Shih Tzu 10
Bulldog 10
Chihuahua 9
Terrier (unspecified) 8

Associated Drugs

Milbemycin Oxime + Spinosad 264
Spinosad 27
Ivermectin 19
Afoxolaner 14
Oclacitinib Maleate 11
Cyclosporine 10
Ivermectin + Pyrantel As Pamoate Salt 8
Milbemycin Oxime + Praziquantel 7
Lotilaner 7
Enrofloxacin 6
Rabacfosadine 6
Imidacloprid + Moxidectin 5
Fluralaner Chew Tablets 5
Trilostane 4
Prednisolone 4
Cyclosporine A 4
Lufenuron + Milbemycin Oxime 4
Vaccines (Unknown) 4
Prednisone 4
Rabacfosadine Succinate 4

Data Summary

Metric Value
Total reports referencing reaction 333
Reports with fatal outcome 18
Case-fatality rate (reported events) 540.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 941.

Dermatosis NOS Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 333 adverse event reports that reference Dermatosis NOS as a reaction term, including 18 reports with a death outcome — a 540.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 941, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Dermatosis NOS appears most frequently in reports for Dog (309 reports), Cat (16 reports), Human (4 reports) — with Dog dominating at 309 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (39), Dog (unknown) (30), Pit Bull (24). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Dermatosis NOS are Milbemycin Oxime + Spinosad (264 reports), Spinosad (27 reports), Ivermectin (19 reports), Afoxolaner (14 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 264 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial